Tetrachloroethene

Ontology mapping

Primary identifier: CHEBI:17300
Ontology label: tetrachloroethene
kg-microbe node: CHEBI:17300

Cellular metabolic roles

Role
ELECTRON_ACCEPTOR
Confidence
0.6
Evidence
- Reference type
  COMPUTATIONAL_PREDICTION
  Reference text
  Assigned by in-session Claude reasoning (no external API)
  Curator note
  Provisional in-session LLM role assignment; review recommended.
- Reference type
  PEER_REVIEWED_PUBLICATION
  Doi
  10.1128/AEM.65.7.3108-3113.1999
  Pmid
  10388710
  Url
  https://pmc.ncbi.nlm.nih.gov/articles/PMC91463/
  Reference text
  Maymo-Gatell et al. (1999). Reductive dechlorination of chlorinated ethenes and 1,2-dichloroethane by Dehalococcoides ethenogenes 195.
  Curator note
  The study demonstrates growth-linked tetrachloroethene dechlorination by strain 195 with hydrogen supplying electrons. It does not imply equivalent utilization by other Dehalococcoides strains or other microbes.
Metabolic context
Respiratory electron acceptor for Dehalococcoides ethenogenes strain 195 during anaerobic reductive dechlorination with hydrogen as electron donor.

Synonyms (9)

Synonym	Type	Source
1,1,2,2-tetrachloroethylene	EXACT_SYNONYM	kg_microbe
PCE	EXACT_SYNONYM	kg_microbe
PERC	EXACT_SYNONYM	kg_microbe
PERK	EXACT_SYNONYM	kg_microbe
Perchloroethylene	EXACT_SYNONYM	kg_microbe
Tetrachloraethen	EXACT_SYNONYM	kg_microbe
ethylene tetrachloride	EXACT_SYNONYM	kg_microbe
tetrachlorethylene	EXACT_SYNONYM	kg_microbe
tetrachloroethylene	EXACT_SYNONYM	kg_microbe

Chemical properties

Cas rn: 127-18-4
Data source: PubChem API
Retrieval date: 2026-04-05T19:54:01.253545+00:00
Molecular formula: C2Cl4
Inchi: InChI=1S/C2Cl4/c3-1(4)2(5)6
Smiles: ClC(Cl)=C(Cl)Cl

Evidence (1)

DATABASE_MATCH via CultureMech

Imported from CultureMech pipeline, quality=DIRECT_MATCH

Occurrence statistics

Total occurrences: 11
Distinct media: 11

Curation history

Timestamp	Curator	Action	New status	Changes
2026-03-09T06:54:18.022301+00:00	import_from_culturemech	IMPORTED	MAPPED	Initial import from CultureMech pipeline
2026-04-05T19:54:01.253581+00:00	fetch_cas_rn_from_pubchem	ADDED_CAS_RN	MAPPED	Added CAS-RN:127-18-4 from PubChem API via name lookup (Tetrachloroethene)
2026-04-18T00:00:00+00:00	cbclaw_kg_microbe_sweep LLM	ADDED_SYNONYMS	MAPPED	Added 9 synonyms from kg-microbe P4.4 enrichment: 1,1,2,2-tetrachloroethylene, PCE, PERC, PERK, Perchloroethylene, ... (4 more)
2026-05-01T07:35:36.563051+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:08:32.633467+00:00	auto_classify_ingredient_type	AUTO_BACKFILL_CHEBI_CHEMISTRY		molecular_formula=C2Cl4; inchi=InChI=1S/C2Cl4/c3-1(4)2(5)6; smiles=ClC(Cl)=C(Cl)Cl
2026-05-02T03:12:18.776089+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula))
2026-06-09T04:56:30.248248+00:00	claude_in_session_curation	ANNOTATED		Added media role: ELECTRON_ACCEPTOR (confidence: 0.60)
2026-07-20T00:00:00+00:00	migrate_media_roles_to_facets	ANNOTATED		Migrated legacy media_roles to role facets (#128): ELECTRON_ACCEPTOR -> cellular_metabolic_roles.ELECTRON_ACCEPTOR
2026-08-27T03:16:39.519945+00:00	refresh_occurrence_statistics	CORRECTED		occurrence_statistics 8/8 -> 11/11 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]
2026-09-22T02:06:34+00:00	codex_issue_710_semantic_evidence_review LLM	CORRECTED_ROLE_EVIDENCE		Added inspected primary-publication support and bounded organism/condition context to the cellular metabolic role (#710). Retained original computational provenance and confidence. See reports/semantic_review_20260921/resolution/roles/cellular-role-plan.json for the assertion-specific interpretation.