Ontology mapping
- Primary identifier
-
CHEBI:49105 - Ontology label
- thiamine hydrochloride
- kg-microbe node
CHEBI:49105
Nutritional roles
- Role
- VITAMIN_SOURCE
- Confidence
- 1.0
- Evidence
- Reference text
- CultureMech database (1647 occurrences as 'Vitamin')
- Reference type
- DATABASE_ENTRY
- Url
- https://github.com/CultureBotAI/CultureMech
- Excerpt
- Role: Vitamin; Properties: Defined component, Simple component, Organic compound
- Curator note
- Widespread use in media formulations (1647 occurrences). High confidence based on 'Defined component' property.
Synonyms (26)
| Synonym | Type | Source | Occurrences |
|---|---|---|---|
| Role: Vitamin; Properties: Organic compound, Defined component, Simple component | RAW_TEXT | CultureMech | |
| Thiamine・HCl | EXACT | manual | |
| Thiamine·HCl | EXACT | manual | |
| 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride | EXACT_SYNONYM | kg_microbe | |
| 3-[(4-azaniumyl-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium dichloride | EXACT_SYNONYM | kg_microbe | |
| Thiamin HCl | EXACT_SYNONYM | kg_microbe | |
| Thiamin-HCl | EXACT_SYNONYM | kg_microbe | |
| Thiamine Dihydrochloride | EXACT_SYNONYM | kg_microbe | |
| Thiamine HCl (B ) - | EXACT_SYNONYM | kg_microbe | |
| Thiamine HCl (Vitamin B ) | EXACT_SYNONYM | kg_microbe | |
| Thiamine hydrochloride | EXACT_SYNONYM | kg_microbe | |
| Thiamine-HCl | EXACT_SYNONYM | kg_microbe | |
| thiamin dichloride | EXACT_SYNONYM | kg_microbe | |
| thiamin hydrochloride | EXACT_SYNONYM | kg_microbe | |
| thiamine chloride hydrochloride | EXACT_SYNONYM | kg_microbe | |
| thiamine dichloride | EXACT_SYNONYM | kg_microbe | |
| thiamine(2+) dichloride | EXACT_SYNONYM | kg_microbe | |
| thiaminium chloride hydrochloride | EXACT_SYNONYM | kg_microbe | |
| Role: Vitamin; Properties: Defined component, Simple component, Organic compound | RAW_TEXT | CultureMech | |
| Role: Vitamin; Properties: Simple component, Organic compound, Defined component | RAW_TEXT | CultureMech | |
| Thiamine HCl | EXACT_SYNONYM | kg_microbe | |
| Role: Vitamin; Properties: Defined component, Organic compound, Simple component | RAW_TEXT | CultureMech | |
| Role: Growth factor | RAW_TEXT | CultureMech | |
| Thiamine HCl (Vitamin B1) | RAW_TEXT | merged_from_unmapped_duplicate_review_2026_05_11 | |
| Thiamine . HCl | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv | |
| Thiamine・HCl (see below) | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv |
Chemical properties
- Cas rn
- 67-03-8
- Data source
- CultureBotHT compounds_to_cas.csv
- Retrieval date
- 2026-04-05T21:48:45.884113+00:00
- Molecular formula
- C12H17N4OS.Cl.HCl
- Inchi
- InChI=1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
- Smiles
- Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1.Cl.[Cl-]
Evidence (2)
DATABASE_MATCH
via CultureMech
Imported from CultureMech pipeline, quality=DIRECT_MATCH
MS-8P medium consisted of Murashige and Skoog salts without NH4NO3, 1 mg l-1 thiamine HCl, 100 mg l-1 myo-inositol, 3.1 g l-1 glutamine and 8P organic addenda.
Auto-proposed; curator should rephrase or remove.
Occurrence statistics
- Total occurrences
- 2,009
- Distinct media
- 1,996
Curation history
| Timestamp | Curator | Action | New status | Changes |
|---|---|---|---|---|
| 2026-03-09T06:54:18.022301+00:00 | import_from_culturemech | IMPORTED | MAPPED | Initial import from CultureMech pipeline |
| 2026-04-05T21:48:45.874834+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:67-03-8 from CultureBotHT compounds_to_cas.csv (matched: Thiamine-HCl) |
| 2026-04-05T21:48:45.876758+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:67-03-8 from CultureBotHT compounds_to_cas.csv (matched: thiamine-HCl) |
| 2026-04-05T21:48:45.884115+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:67-03-8 from CultureBotHT compounds_to_cas.csv (matched: Thiamine HCl) |
| 2026-04-05T21:48:45.889030+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:67-03-8 from CultureBotHT compounds_to_cas.csv (matched: Thiamine·HCl) |
| 2026-04-05T23:47:05.776154+00:00 | fetch_cas_rn_with_preprocessing | ADDED_CAS_RN | MAPPED | Added CAS-RN:67-03-8 from PubChem API (ontology label) via name preprocessing (Thiamin-HCl) |
| 2026-04-05T23:47:06.549770+00:00 | fetch_cas_rn_with_preprocessing | ADDED_CAS_RN | MAPPED | Added CAS-RN:67-03-8 from PubChem API (ontology label) via name preprocessing (Thiamine dihydrochloride) |
| 2026-04-05T23:47:06.968804+00:00 | fetch_cas_rn_with_preprocessing | ADDED_CAS_RN | MAPPED | Added CAS-RN:67-03-8 from PubChem API (ontology label) via name preprocessing (thiamine hydrochloride) |
| 2026-04-09T00:32:50.689620+00:00 | enrich_mim_cas_rn_batch | CAS_RN_ADDED | MAPPED | Added CAS-RN 67-03-8 from PubChem (via CHEBI:49105) |
| 2026-04-17T12:00:00+00:00 | synonym_expansion_cbclaw LLM | ADDED_SYNONYMS | MAPPED | Added 2 synonyms (unicode dot variants) for unmapped CultureMech surface forms |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 15 synonyms from kg-microbe P4.4 enrichment: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride, 3-[(4-azaniumyl-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium dichloride, Thiamin HCl, Thiamin-HCl, Thiamine Dihydrochloride, ... (10 more) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 16 synonyms from kg-microbe P4.4 enrichment: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride, 3-[(4-azaniumyl-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium dichloride, Thiamin HCl, Thiamin-HCl, Thiamine Dihydrochloride, ... (11 more) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 15 synonyms from kg-microbe P4.4 enrichment: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride, 3-[(4-azaniumyl-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium dichloride, Thiamin HCl, Thiamine Dihydrochloride, Thiamine HCL, ... (10 more) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 15 synonyms from kg-microbe P4.4 enrichment: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride, 3-[(4-azaniumyl-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium dichloride, Thiamin HCl, Thiamin-HCl, Thiamine HCL, ... (10 more) |
| 2026-04-19T07:39:23.955331+00:00 | audit_mim_merge | MERGED_FROM_DUPLICATES | MAPPED | Absorbed 7 duplicate MIM record(s) into this one: Thiamine-hcl.yaml, Thiamine_Hydrochloride.yaml, Thiamin-hcl.yaml, Thiaminehcl.yaml, Thiamine_Dihydrochloride.yaml, Thiamine_Hydrochloride_2.yaml, Thiamine-hcl_2.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break. |
| 2026-05-01T07:35:36.612329+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (CHEBI primary) | |
| 2026-05-01T08:08:32.687242+00:00 | auto_classify_ingredient_type | AUTO_BACKFILL_CHEBI_CHEMISTRY | molecular_formula=C12H17N4OS.Cl.HCl; inchi=InChI=1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8); smiles=Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1.Cl.[Cl-] | |
| 2026-05-01T08:09:48.135484+00:00 | auto_classify_ingredient_type | APPLY_EVIDENCE_PROPOSAL | added pmid=30744227 from propose-evidence batch | |
| 2026-05-02T03:12:18.844313+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula)) | |
| 2026-05-11T06:02:00Z | mediaingredientmech-agentic-curation LLM | ABSORBED_UNMAPPED_DUPLICATE | MAPPED | Absorbed duplicate unmapped record Thiamine_HCl_(Vitamin_B1).yaml (UNMAPPED_0617); the parenthetical vitamin label is source context and the identity is thiamine hydrochloride CHEBI:49105. |
| 2026-05-29T23:35:36.113159+00:00 | extract_roles_from_synonyms | ANNOTATED | Added media role: VITAMIN_SOURCE (confidence: 1.00) | |
| 2026-06-09T05:23:46.843315+00:00 | correct_stale_ontology_labels.py | CORRECTED | ontology_label 'Thiamine HCl' -> 'thiamine hydrochloride': synced to canonical CHEBI label (preferred_term 'Thiamine HCl' unchanged). | |
| 2026-07-20T00:00:00+00:00 | migrate_media_roles_to_facets | ANNOTATED | Migrated legacy media_roles to role facets (#128): VITAMIN_SOURCE -> nutritional_roles.VITAMIN_SOURCE | |
| 2026-08-27T03:16:39.519961+00:00 | refresh_occurrence_statistics | CORRECTED | occurrence_statistics 136/1647 -> 1996/2009 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257] | |
| 2026-08-30T04:48:06.233536+00:00 | claude_culturemech_alias_backfill | ADDED_SYNONYMS | Added 2 CultureMech recipe surface form(s) that folded onto this record's published label but were absent from MIM's label index, so CultureMech could not resolve them: 'Thiamine . HCl' (x10 CultureMech mentions); 'Thiamine・HCl (see below)' (x1 CultureMech mentions). Source: culturemech:output/ingredient_occurrences.tsv. |