Thiosulfate

Ontology mapping

Primary identifier: CHEBI:26977
Ontology label: thiosulfate

Cellular metabolic roles

Role
ELECTRON_DONOR
Confidence
0.6
Evidence
- Reference type
  COMPUTATIONAL_PREDICTION
  Reference text
  Assigned by in-session Claude reasoning (no external API)
  Curator note
  Provisional in-session LLM role assignment; review recommended.
- Reference type
  PEER_REVIEWED_PUBLICATION
  Doi
  10.1128/AEM.02111-16
  Pmid
  27565613
  Url
  https://pmc.ncbi.nlm.nih.gov/articles/PMC5066360/
  Reference text
  Levy et al. (2016). Chlorobaculum tepidum modulates amino acid composition in response to energy availability.
  Curator note
  The study varies thiosulfate as an electron donor and measures growth responses. This is organism-scoped evidence, not an assertion that all microbes use thiosulfate.
Metabolic context
Electron donor for Chlorobaculum tepidum WT2321 during illuminated, anoxic growth in thiosulfate-supplemented Pf-7 medium.

Synonyms (7)

Synonym	Type	Source
ester of thiosulfuric acid	EXACT_SYNONYM	kg_microbe
esters of thiosulfuric acid	EXACT_SYNONYM	kg_microbe
thiosulfate ester	EXACT_SYNONYM	kg_microbe
thiosulfate esters	EXACT_SYNONYM	kg_microbe
thiosulfates	EXACT_SYNONYM	kg_microbe
thiosulphates	EXACT_SYNONYM	kg_microbe
Role: Growth factor; Properties: Defined component, Inorganic compound, Simple component	RAW_TEXT	CultureMech

Evidence (1)

DATABASE_MATCH via CultureMech

Imported from CultureMech pipeline, quality=DIRECT_MATCH

Occurrence statistics

Total occurrences: 6
Distinct media: 6

Curation history

Timestamp	Curator	Action	New status	Changes
2026-03-09T06:54:18.022301+00:00	import_from_culturemech	IMPORTED	MAPPED	Initial import from CultureMech pipeline
2026-04-18T00:00:00+00:00	cbclaw_kg_microbe_sweep LLM	ADDED_SYNONYMS	MAPPED	Added 6 synonyms from kg-microbe P4.4 enrichment: ester of thiosulfuric acid, esters of thiosulfuric acid, thiosulfate ester, thiosulfate esters, thiosulfates, ... (1 more)
2026-04-19T07:39:23.955331+00:00	audit_mim_merge	MERGED_FROM_DUPLICATES	MAPPED	Absorbed 1 duplicate MIM record(s) into this one: Thiosulfate_2.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break.
2026-05-01T07:35:36.639393+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-02T03:12:18.878158+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-06-09T04:56:30.248256+00:00	claude_in_session_curation	ANNOTATED		Added media role: ELECTRON_DONOR (confidence: 0.60)
2026-06-09T05:23:46.843790+00:00	correct_stale_ontology_labels.py	CORRECTED		ontology_label 'Thiosulfate' -> 'thiosulfate': synced to canonical CHEBI label (preferred_term 'Thiosulfate' unchanged).
2026-07-20T00:00:00+00:00	migrate_media_roles_to_facets	ANNOTATED		Migrated legacy media_roles to role facets (#128): ELECTRON_DONOR -> cellular_metabolic_roles.ELECTRON_DONOR
2026-08-27T03:16:39.519970+00:00	refresh_occurrence_statistics	CORRECTED		occurrence_statistics 4/4 -> 6/6 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]
2026-09-22T02:06:34+00:00	codex_issue_710_semantic_evidence_review LLM	CORRECTED_ROLE_EVIDENCE		Added inspected primary-publication support and bounded organism/condition context to the cellular metabolic role (#710). Retained original computational provenance and confidence. See reports/semantic_review_20260921/resolution/roles/cellular-role-plan.json for the assertion-specific interpretation.