Ontology mapping
- Primary identifier
-
CHEBI:9754 - Ontology label
- tris
- kg-microbe node
CHEBI:9754
Physicochemical roles
- Role
- BUFFER
- Confidence
- 1.0
- Evidence
- Reference type
- DATABASE_ENTRY
- Reference text
- Imported from CultureMech pipeline
- Curator note
- Original role text: Buffer
Synonyms (34)
| Synonym | Type | Source | Occurrences |
|---|---|---|---|
| Role: Buffer; Properties: Defined component, Organic compound, Simple component | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Defined component, Simple component, Organic compound | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Organic compound, Defined component, Simple component | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Organic compound, Simple component, Defined component | RAW_TEXT | CultureMech | |
| 1,1,1-tris(hydroxymethyl)methanamine | EXACT_SYNONYM | kg_microbe | |
| 2-Amino-2-(hydroxymethyl)-1,3-propanediol | EXACT_SYNONYM | kg_microbe | |
| 2-amino-2-(hydroxymethyl)propane-1,3-diol | EXACT_SYNONYM | kg_microbe | |
| THAM | EXACT_SYNONYM | kg_microbe | |
| Tris (hydroxymethyl aminomethane) | EXACT_SYNONYM | kg_microbe | |
| Tris [tris(hydroxymethyl)aminomethane] | EXACT_SYNONYM | kg_microbe | |
| Tris amino | EXACT_SYNONYM | kg_microbe | |
| Tris buffer | EXACT_SYNONYM | kg_microbe | |
| Tris buffer 1M | EXACT_SYNONYM | kg_microbe | |
| Tris hydrochloride | EXACT_SYNONYM | kg_microbe | |
| Tris(hydroxymethyl)aminomethane | EXACT_SYNONYM | kg_microbe | |
| Tris-base | EXACT_SYNONYM | kg_microbe | |
| Tris [tris(hydroxymethyl)aminomethane] | EXACT_SYNONYM | kg_microbe | |
| Trizma | EXACT_SYNONYM | kg_microbe | |
| Trizma Base pH | EXACT_SYNONYM | kg_microbe | |
| Trometamol | EXACT_SYNONYM | kg_microbe | |
| Tromethamine | EXACT_SYNONYM | kg_microbe | |
| aminotris(hydroxymethyl)methane | EXACT_SYNONYM | kg_microbe | |
| nitrilotriacetic acid trisodium salt | EXACT_SYNONYM | kg_microbe | |
| Tris | EXACT_SYNONYM | merged_from_duplicate_mim_record | |
| Tris(hydroxymethyl)methylamine | EXACT_SYNONYM | merged_from_duplicate_mim_record | |
| Role: Buffer; Properties: Simple component, Organic compound, Defined component | RAW_TEXT | CultureMech | |
| Tris-HCl buffer | EXACT | manual | |
| Tris HCl | EXACT | manual | |
| Role: Buffer; Properties: Defined component, Complex component, Solution | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Complex component, Defined component, Solution | RAW_TEXT | CultureMech | |
| Trizma Base pH 8.2 | RAW_TEXT | CultureMech | |
| Tris base (buffer) | RAW_TEXT | merged_from_unmapped_duplicate_review_2026_05_11 | |
| Tris (hydroxymethyl) aminomethane | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv | |
| Tris・HCl | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv |
Chemical properties
- Cas rn
- 77-86-1
- Data source
- PubChem (via CHEBI:9754)
- Retrieval date
- 2026-04-09T00:32:50.689620+00:00
- Molecular formula
- C4H11NO3
- Inchi
- InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
- Smiles
- NC(CO)(CO)CO
Evidence (1)
DATABASE_MATCH
via CultureMech
Imported from CultureMech pipeline, quality=DIRECT_MATCH
Occurrence statistics
- Total occurrences
- 212
- Distinct media
- 210
Curation history
| Timestamp | Curator | Action | New status | Changes |
|---|---|---|---|---|
| 2026-03-09T06:54:18.022301+00:00 | import_from_culturemech | IMPORTED | MAPPED | Initial import from CultureMech pipeline |
| 2026-04-05T19:54:09.046241+00:00 | fetch_cas_rn_from_pubchem | ADDED_CAS_RN | MAPPED | Added CAS-RN:77-86-1 from PubChem API via name lookup (Tris) |
| 2026-04-05T21:48:45.909752+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:77-86-1 from CultureBotHT compounds_to_cas.csv (matched: TRIS) |
| 2026-04-05T21:48:45.913904+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:77-86-1 from CultureBotHT compounds_to_cas.csv (matched: Tris buffer 1M) |
| 2026-04-05T21:48:45.915929+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:77-86-1 from CultureBotHT compounds_to_cas.csv (matched: Tris(hydroxymethyl)aminomethane) |
| 2026-04-09T00:32:50.689620+00:00 | enrich_mim_cas_rn_batch | CAS_RN_ADDED | MAPPED | Added CAS-RN 77-86-1 from PubChem (via CHEBI:9754) |
| 2026-04-17T12:00:00+00:00 | synonym_expansion_cbclaw LLM | ADDED_SYNONYMS | MAPPED | Added 2 synonyms for unmapped CultureMech surface forms |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 19 synonyms from kg-microbe P4.4 enrichment: 1,1,1-tris(hydroxymethyl)methanamine, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, 2-amino-2-(hydroxymethyl)propane-1,3-diol, THAM, Tris (hydroxymethyl aminomethane), ... (14 more) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 20 synonyms from kg-microbe P4.4 enrichment: 1,1,1-tris(hydroxymethyl)methanamine, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, 2-amino-2-(hydroxymethyl)propane-1,3-diol, THAM, Tris (hydroxymethyl aminomethane), ... (15 more) |
| 2026-04-19T07:39:23.955331+00:00 | audit_mim_merge | MERGED_FROM_DUPLICATES | MAPPED | Absorbed 6 duplicate MIM record(s) into this one: Tris.yaml, Tris_Hydroxymethylaminomethane.yaml, Tris_Buffer.yaml, Tris_Hydroxymethylmethylamine.yaml, Tris_Buffer_1m.yaml, Tris_2.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break. |
| 2026-05-01T07:35:36.731808+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (CHEBI primary) | |
| 2026-05-01T08:08:32.817475+00:00 | auto_classify_ingredient_type | AUTO_BACKFILL_CHEBI_CHEMISTRY | molecular_formula=C4H11NO3; inchi=InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2; smiles=NC(CO)(CO)CO | |
| 2026-05-02T03:12:19.013086+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula)) | |
| 2026-05-05T00:00:00+00:00 | ingredient_mapping_review_2026_05_05 | MERGED | MAPPED | Absorbed duplicate record Trizma_Base_Ph.yaml (UNMAPPED_0090) into Tris_Base.yaml; source occurrence counts and synonyms were merged. Trizma Base pH text is preparation context; identity is Tris base CHEBI:9754. |
| 2026-05-11T06:02:00Z | mediaingredientmech-agentic-curation LLM | ABSORBED_UNMAPPED_DUPLICATE | MAPPED | Absorbed duplicate unmapped record Tris_Base_(buffer).yaml (UNMAPPED_0620); buffer is usage context and the identity is Tris base CHEBI:9754. |
| 2026-05-29T23:35:36.113237+00:00 | extract_roles_from_synonyms | ANNOTATED | Added media role: BUFFER (confidence: 1.00) | |
| 2026-06-09T05:23:46.846733+00:00 | correct_stale_ontology_labels.py | CORRECTED | ontology_label 'Tris base' -> 'tris': synced to canonical CHEBI label (preferred_term 'Tris base' unchanged). | |
| 2026-07-20T00:00:00+00:00 | migrate_media_roles_to_facets | ANNOTATED | Migrated legacy media_roles to role facets (#128): BUFFER -> physicochemical_roles.BUFFER | |
| 2026-08-27T03:16:39.520015+00:00 | refresh_occurrence_statistics | CORRECTED | occurrence_statistics 61/61 -> 210/212 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257] | |
| 2026-08-30T04:48:06.233536+00:00 | claude_culturemech_alias_backfill | ADDED_SYNONYMS | Added 2 CultureMech recipe surface form(s) that folded onto this record's published label but were absent from MIM's label index, so CultureMech could not resolve them: 'Tris (hydroxymethyl) aminomethane' (x4 CultureMech mentions); 'Tris・HCl' (x1 CultureMech mentions). Source: culturemech:output/ingredient_occurrences.tsv. |