Vitamin B12

Ontology mapping

Primary identifier: CHEBI:176843
Ontology label: vitamin B12
kg-microbe node: CHEBI:176843

Nutritional roles

Role
VITAMIN_SOURCE
Confidence
1.0
Evidence
- Reference type
  DATABASE_ENTRY
  Reference text
  Imported from CultureMech pipeline
  Curator note
  Original role text: Vitamin Source

Synonyms (23)

Synonym	Type	Source
(add after autoclaving)	RAW_TEXT	CultureMech
Role: Vitamin; Properties: Defined component, Organic compound, Simple component	RAW_TEXT	CultureMech
Role: Vitamin; Properties: Defined component, Simple component, Organic compound	RAW_TEXT	CultureMech
Role: Vitamin; Properties: Organic compound, Defined component, Simple component	RAW_TEXT	CultureMech
Role: Vitamin; Properties: Organic compound, Simple component, Defined component	RAW_TEXT	CultureMech
CN-Cbl	EXACT_SYNONYM	kg_microbe
CO-CYANOCOBALAMIN	EXACT_SYNONYM	kg_microbe
Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-cyanocobamide	EXACT_SYNONYM	kg_microbe
Cyanocob(III)alamin	EXACT_SYNONYM	kg_microbe
Cyanocobalamin (B )	EXACT_SYNONYM	kg_microbe
Cyanocobalamin (Vitamin B )	EXACT_SYNONYM	kg_microbe
Cyanocobalamine	EXACT_SYNONYM	kg_microbe
Cyanocobalamin in	EXACT_SYNONYM	kg_microbe
Dicopac	EXACT_SYNONYM	kg_microbe
Vitamin B12 complex	EXACT_SYNONYM	kg_microbe
Vitamin B12 (4)	EXACT_SYNONYM	kg_microbe
Vitamin B12 (8)	EXACT_SYNONYM	kg_microbe
Vitamin B12 (9)	EXACT_SYNONYM	kg_microbe
vitamin B-12	EXACT_SYNONYM	kg_microbe
vitamin B12 vitamer	EXACT_SYNONYM	kg_microbe
VitaminB12	EXACT_SYNONYM	merged_from_duplicate_mim_record
Vitamin B12 (cyanocobalamin)	EXACT_SYNONYM	unmapped_ols_exact_audit
Vitamine B12	EXACT_SYNONYM	unmapped_duplicate_review_2026_05_11

Rejected enrichment labels (1)

Provenance-only candidates: these are not synonyms and do not resolve to this record.

Rejected label	Disposition	Source	Occurrences
Cyanocobalamin	REJECTED_LABEL	kg_microbe

Chemical properties

Cas rn: 68-19-9
Data source: CultureBotHT compounds_to_cas.csv
Retrieval date: 2026-04-05T21:48:45.943272+00:00

Evidence (2)

DATABASE_MATCH via CultureMech

Imported from CultureMech pipeline, quality=DIRECT_MATCH

LITERATURE SUPPORTvia PubMed search ('Vitamin B12') PMID:37093107

Circulating vitamin B12 concentrations during pregnancy are associated with offspring health.

Auto-proposed; curator should rephrase or remove.

Occurrence statistics

Total occurrences: 2,408
Distinct media: 2,406

Curation history

Timestamp	Curator	Action	New status	Changes
2026-03-09T06:54:18.022301+00:00	import_from_culturemech	IMPORTED	MAPPED	Initial import from CultureMech pipeline
2026-04-05T19:54:13.637640+00:00	fetch_cas_rn_from_pubchem	ADDED_CAS_RN	MAPPED	Added CAS-RN:68-19-9 from PubChem API via name lookup (vitamin B12)
2026-04-05T21:48:45.943274+00:00	fetch_cas_rn_from_culturebot_csv	ADDED_CAS_RN	MAPPED	Added CAS-RN:68-19-9 from CultureBotHT compounds_to_cas.csv (matched: Vitamin B12)
2026-04-05T21:48:45.950352+00:00	fetch_cas_rn_from_culturebot_csv	ADDED_CAS_RN	MAPPED	Added CAS-RN:68-19-9 from CultureBotHT compounds_to_cas.csv (matched: VitaminB12)
2026-04-18T00:00:00+00:00	cbclaw_kg_microbe_sweep LLM	ADDED_SYNONYMS	MAPPED	Added 16 synonyms from kg-microbe P4.4 enrichment: CN-Cbl, CO-CYANOCOBALAMIN, Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-cyanocobamide, Cyanocob(III)alamin, Cyanocobalamin, ... (11 more)
2026-04-19T07:32:32.653265+00:00	audit_fix_mim_wrong	FIXED_MIM_WRONG_CHEBI	MAPPED	Swapped CHEBI:17439 → CHEBI:176843 (vitamin B12) — OLS round-trip confirmed MIM's prior CHEBI was mismatched to preferred_term='Vitamin B12'; kg-microbe proposal adopted.
2026-04-19T07:39:23.955331+00:00	audit_mim_merge	MERGED_FROM_DUPLICATES	MAPPED	Absorbed 2 duplicate MIM record(s) into this one: Vitamin_B12_2.yaml, Vitaminb12.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break.
2026-05-01T07:35:36.866878+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:09:48.147543+00:00	auto_classify_ingredient_type	APPLY_EVIDENCE_PROPOSAL		added pmid=37093107 from propose-evidence batch
2026-05-02T03:12:19.203972+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-06T00:00:00+00:00	unmapped_ols_exact_audit	MERGED_FROM_UNMAPPED_DUPLICATE	MAPPED	Added exact synonym "Vitamin B12 (cyanocobalamin)" and retired duplicate unmapped record Vitamin_B12_(cyanocobalamin).yaml after OLS exact match to CHEBI:176843; aligned kg_microbe_node_id with the corrected ontology mapping.
2026-05-11T08:27:00Z	mediaingredientmech-agentic-curation LLM	ABSORBED_UNMAPPED_DUPLICATE	MAPPED	Absorbed duplicate unmapped record Vitamine_B12.yaml (UNMAPPED_0570); "Vitamine B12" is a spelling variant of the existing mapped vitamin B12 identity CHEBI:176843.
2026-05-29T23:35:36.113331+00:00	extract_roles_from_synonyms	ANNOTATED		Added media role: VITAMIN_SOURCE (confidence: 1.00)
2026-07-20T00:00:00+00:00	migrate_media_roles_to_facets	ANNOTATED		Migrated legacy media_roles to role facets (#128): VITAMIN_SOURCE -> nutritional_roles.VITAMIN_SOURCE
2026-08-27T03:16:39.520138+00:00	refresh_occurrence_statistics	CORRECTED		occurrence_statistics 55/2331 -> 2406/2408 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]
2026-09-24T07:48:22.717101+00:00	claude LLM	REJECTED_WRONG_SUBSTANCE_SYNONYMS	MAPPED	Retyped REJECTED_LABEL: 'Cyanocobalamin' (EXACT_SYNONYM): the member's name on the vitamin B12 class record CHEBI:176843; Cyanocobalamin has its own record (#669). Kept as provenance only; it must not resolve, be exported, or enter the SSSOM other column.