2-methyladeninyl cobamide

UNMAPPED_0182 chemically defined UNMAPPED

Ontology mapping

Primary identifier: UNMAPPED_0182
Notes: Imported from CultureBotHT (compounds_to_cas.csv (no CAS-RN)). No CAS-RN or CHEBI mapping available; curator review needed. Reviewed on 2026-05-11 as a specific cobamide variant; not identity-mapped to generic cobamide or cobalamin.

Synonyms (5)

Synonym	Type	Source	Occurrences
2-methyladeninyl cobamide	RAW_TEXT	culturebotht
2-methyladeninylcobamide	EXACT_SYNONYM	edison_deep_research
[2-MeAde]Cba	ABBREVIATION	edison_deep_research
Factor A	COMMON_NAME	edison_deep_research
Co-cyano-(2-methyladenin-7-yl)cobamide	SYSTEMATIC_NAME	edison_deep_research

Occurrence statistics

Total occurrences: 0
Distinct media: 0

Curation history

Timestamp	Curator	Action	New status	Changes
2026-04-29T06:51:33.117170+00:00	audit_add_remaining_culturebotht	CREATED_AS_UNMAPPED	UNMAPPED	Imported from CultureBotHT (compounds_to_cas.csv (no CAS-RN)). No CAS-RN or CHEBI mapping available; curator review needed.
2026-05-11T08:12:15Z	mediaingredientmech-agentic-curation LLM	REVIEWED_COBAMIDE_VARIANT	UNMAPPED	Classified as a single cobamide-family ingredient and left unmapped because no exact local ontology identity for the 2-methyladeninyl lower-ligand variant was verified.
2026-06-14T00:00:00+00:00	deep-research-ingredient-edison LLM	RESEARCHED_IDENTITY	UNMAPPED	Edison/PaperQA3 deep research (8 citations) confirms this is a specific cobamide corrinoid with lower ligand = 2-methyladenine (legacy name "Factor A", cyano form Co-cyano-(2-methyladenin-7-yl)cobamide, CCDC:217275). No source-backed CHEBI/CAS identifier exists, and the generic label is upper-ligand-ambiguous — KEEP UNMAPPED (do NOT map to cobalamin/B12: different lower ligand). Enriched with source-backed synonyms.
2026-08-06T00:00:00+00:00	edison_literature_identity LLM	ANNOTATED		Edison LITERATURE (PaperQA3) identity research; report at research/ingredients/2-methyladeninyl_Cobamide-edison-literature.md (local artifact — research/ is gitignored, so the findings are quoted here rather than linked). Report verdict: Recommended interpretation: a specific purinyl cobamide defined by its lower ligand, 2-methyladenine, attached through N7, rather than a mixture, buffer, extract, or commercial formulation. Modern biochemical literature abbreviates it [2-MeAde]Cba and reports purification of the individual cobamide by HPLC, supporting treatment as a single-ingredient cobamide identity rather than a for No ontology CURIE was proposed. Recorded as provenance only — no grounding applied from this run. Edison's recommendations are deliberately conservative, and a plausible identifier promoted by a mechanism that never decided anything is what #203 and #263 exist to undo. Any CURIE above is a curator's to accept or reject.