Tetrazolium

Ontology mapping

Primary identifier: UNMAPPED_0734
Notes: Imported from microbedecoder (source_id=kgmicrobe.trait:tetrazolium); no CAS-RN or CHEBI/NCIT match. Curator review needed. Retired as an ingredient record (#213/#308): a bare family name reporting a reduction readout. ChEBI has no generic tetrazolium class — only specific salts — and MicrO models the readout as MICRO:0000270 'tetrazolium reduction assay'. The salt actually used in bacterial media, TTC, is already a record: `2,3,5-Triphenyltetrazolium chloride` (CHEBI:78019). Grounding the bare family name to one of its members is the error #368 records for sulfur. Not mapped, because every substrate CURIE it could be grounded to is already the primary key of a live record — in MIM the identifier IS the ontology CURIE, so a mapping here would mint a duplicate rather than add coverage. No synonym is folded onto those records either: this label names a reaction or a splice, not the substance, and asserting the synonymy would make label_index resolve it to something it does not denote.

Synonyms (1)

Synonym	Type	Source	Occurrences
Tetrazolium	RAW_TEXT	microbedecoder

Occurrence statistics

Total occurrences

Distinct media

Source occurrences

Source
microbedecoder
Count
2
Source columns
BacDive_Metabolite_utilization

Curation history

Timestamp	Curator	Action	New status	Changes
2026-08-04T02:54:09.684805+00:00	audit_import_ingredients[microbedecoder]	CREATED_AS_UNMAPPED	UNMAPPED	Imported from microbedecoder (source_id=kgmicrobe.trait:tetrazolium); no CAS-RN or CHEBI/NCIT match. Curator review needed.
2026-08-06T00:00:00+00:00	issue_213_residual_triage LLM	FLAGGED_NEEDS_EXPERT	NEEDS_EXPERT	Class-level label. MeSH:D013778 'Tetrazolium Salts' is the closest term and is plausibly what this means in a medium (TTC and relatives), but 'tetrazolium' is NOT a registered synonym of it, so grounding would be inference rather than evidence. Needs a granularity decision. Searched CHEBI, NCIT, FOODON, ENVO, MeSH, BTO and UBERON by label and synonym with normalisation, plus exact queries across all of live OLS4.
2026-08-06T00:00:00+00:00	edison_literature_identity LLM	ANNOTATED		Edison LITERATURE (PaperQA3) identity research; report at research/ingredients/Tetrazolium-edison-literature.md (local artifact — research/ is gitignored, so the findings are quoted here rather than linked). Report verdict: Recommended interpretation: the bare label “Tetrazolium” is an ambiguous chemical-family label, not a uniquely specified media ingredient. The literature describes multiple mono- and ditetrazolium salts with materially different substituents, counterions, solubility, membrane permeability, reduction behavior, and biological effects. Examples include TTC, MTT, INT, CTC, XTT, MTS, WST-1, NBT CURIEs discussed: MESH:D013754. Recorded as provenance only — no grounding applied from this run. Edison's recommendations are deliberately conservative, and a plausible identifier promoted by a mechanism that never decided anything is what #203 and #263 exist to undo. Any CURIE above is a curator's to accept or reject.
2026-08-15T00:00:00+00:00	retire_assay_labels	RETIRED_NOT_AN_INGREDIENT	REJECTED	Retired as an ingredient record (#213/#308): a bare family name reporting a reduction readout. ChEBI has no generic tetrazolium class — only specific salts — and MicrO models the readout as MICRO:0000270 'tetrazolium reduction assay'. The salt actually used in bacterial media, TTC, is already a record: `2,3,5-Triphenyltetrazolium chloride` (CHEBI:78019). Grounding the bare family name to one of its members is the error #368 records for sulfur. Not mapped, because every substrate CURIE it could be grounded to is already the primary key of a live record — in MIM the identifier IS the ontology CURIE, so a mapping here would mint a duplicate rather than add coverage. No synonym is folded onto those records either: this label names a reaction or a splice, not the substance, and asserting the synonymy would make label_index resolve it to something it does not denote.