CellularMetabolicRoleEnum

Name
CellularMetabolicRoleEnum
Description
Role of the ingredient inside or on the cultured microbe(s) — the compound's metabolic fate or biochemical function at the cell level. One of three orthogonal role facets (with NutritionalRoleEnum and PhysicochemicalRoleEnum). Values in this facet are often organism-conditional (e.g. ELECTRON_DONOR applies only for organisms that oxidize the compound for energy; methanol is an electron donor for methylotrophs but only a carbon source for others).
From schema
https://w3id.org/mediaingredientmech
Permissible values
Substrate
Text
SUBSTRATE
Description
Consumed by the organism for biosynthesis, energy, or both (general-purpose substrate role).
Electron donor
Text
ELECTRON_DONOR
Description
Electron donor for chemolithotrophic or heterotrophic energy metabolism (organism-conditional).
Meaning
CHEBI:15022
Electron acceptor
Text
ELECTRON_ACCEPTOR
Description
Terminal electron acceptor for respiration (e.g., nitrate, oxygen, sulfate; organism-conditional).
Meaning
CHEBI:17654
Cofactor
Text
COFACTOR
Description
Acts as an intracellular enzyme cofactor (contrast with NutritionalRoleEnum.COFACTOR_PROVIDER, the supply-side role).
Meaning
CHEBI:23357
Prosthetic group precursor
Text
PROSTHETIC_GROUP_PRECURSOR
Description
Precursor for a covalently-bound cofactor / prosthetic group (e.g., δ-aminolevulinate for heme). Note the mapping below points at the parent role `prosthetic group` — CHEBI has no dedicated `prosthetic group precursor` role class, so the mapping is a hierarchy pointer, not identity.
Mappings
Membrane component
Text
MEMBRANE_COMPONENT
Description
Incorporated into cell membranes (e.g., fatty acids, sterols, isoprenoid lipids).
Osmoprotectant
Text
OSMOPROTECTANT
Description
Accumulated intracellularly to balance external osmotic stress (e.g., glycine betaine, ectoine, trehalose). Organism-conditional — assign only with organism-context evidence (e.g., "glycine betaine is imported and accumulated as an osmoprotectant by <organism>"). NOTE: shares `mappings: CHEBI:25728 (osmolyte)` with PhysicochemicalRoleEnum.OSMOTIC_AGENT. See that value's description for cross-facet guidance.
Mappings
Inducer
Text
INDUCER
Description
Triggers expression of specific genes or pathways when present (e.g., IPTG, arabinose).
Inhibitor
Text
INHIBITOR
Description
Suppresses growth or a specific pathway (e.g., antibiotics targeting cellular processes).
Meaning
CHEBI:35222
Quencher
Text
QUENCHER
Description
Absorbs or dissipates a signal (e.g., quenches fluorescence, radicals, or light).