NaturalProductMech

prodigiosin

naturalproductmech:mibig-d764a5151a MINTED SEEDED

Structure

Standard InChIKeyWKGQSEFBQTWRPT-UUPRNIFOSA-N
SMILESCCCCCC1=C(NC(=C1)/C=C\2/C(=C/C(=C/3\C=CC=N3)/N2)OC)C
Stereochemistryfully defined
Cross-referencespubchem:5351169

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 3

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Serratia sp.
NCBITaxon:616
SOURCE_ASSERTION mibig:BGC0000258 PMID:15528645
Serratia marcescens
NCBITaxon:615
SOURCE_ASSERTION mibig:BGC0000259 PMID:15528645
Hahella chejuensis KCTC 2396
NCBITaxon:349521
SOURCE_ASSERTION mibig:BGC0000260 PMID:17381736

Occurrences 14

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Hahella chejuensis
NCBITaxon:158327
LOTUS DOI:10.1111/J.1365-2672.2006.03172.X
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1007/S10482-012-9772-5
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1007/S11033-018-4324-3
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1007/S11427-017-9117-X
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1099/00221287-131-9-2431
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1128/JB.00017-11
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1007/S10482-012-9772-5
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1007/S11033-018-4324-3
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1007/S11427-017-9117-X
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1099/00221287-131-9-2431
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1128/JB.00017-11
Streptomyces griseoviridis
NCBITaxon:45398
LOTUS DOI:10.1038/JA.2009.27
Streptomyces olivaceus
NCBITaxon:47716
LOTUS DOI:10.1007/BF00411284
Serratia marcescens
NCBITaxon:615
LOTUS DOI:10.1099/MIC.0.27222-0

Biosynthetic gene clusters 3

AccessionHostLocus evidenceGenome
mibig:BGC0000258 Serratia sp.
NCBITaxon:616
CLUSTER_UNSTATED genbank:AJ833001.1
mibig:BGC0000259 Serratia marcescens
NCBITaxon:615
CLUSTER_UNSTATED genbank:AJ833002.1
mibig:BGC0000260 Hahella chejuensis KCTC 2396
NCBITaxon:349521
CLUSTER_UNSTATED genbank:DQ266254.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000258, BGC0000259, BGC0000260. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000258MIBIG3
BGC0000259MIBIG3
BGC0000260MIBIG3

This page is generated from data/natural_products/alkaloids/prodigiosin-2.yaml, which is generated from the committed inventories. Neither is edited by hand.