NaturalProductMech

blasticidin S

CHEBI:15353 EXACT SEEDED antifungal

A blasticidin that is an antibiotic obtained from Streptomyces griseochromogene.

Structure

Standard InChIKeyCXNPLSGKWMLZPZ-ZNIXKSQXSA-N
SMILESCN(C(N)=N)CC[C@H](N)CC(N[C@H]1C=C[C@H](N2C=CC(N)=NC2=O)O[C@@H]1C(O)=O)=O
Stereochemistryfully defined
Cross-referencespubchem:170012

Filing pathway

Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces griseochromogenes
NCBITaxon:68214
SOURCE_ASSERTION mibig:BGC0000874 PMID:12964155

Occurrences 17

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces arginensis
NCBITaxon:1295550
LOTUS DOI:10.1128/AEM.01172-14
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1080/10575639608043253
Streptomyces setonii
NCBITaxon:1911
LOTUS DOI:10.7164/ANTIBIOTICS.42.470
Streptomyces lividans
NCBITaxon:1916
LOTUS DOI:10.1128/AEM.03254-12
Streptomyces morookaense
NCBITaxon:1970
LOTUS DOI:10.1093/OXFORDJOURNALS.JBCHEM.A021929
Streptomyces morookaense
NCBITaxon:1970
LOTUS DOI:10.1263/JBB.101.63
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.1002/CBIC.200300583
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.1016/0045-2068(88)90014-4
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.1016/S0031-9422(00)95133-1
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.1016/S0040-4020(99)01060-1
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.1016/S0040-4039(01)83843-0
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.1021/JA00015A074
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.1021/JA00225A033
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.1021/NP970468O
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.1139/V94-002
Streptomyces griseochromogenes
NCBITaxon:68214
LOTUS DOI:10.7164/ANTIBIOTICS.51.570
Streptomyces griseochromogenes
NCBITaxon:68214
CHEBI PMID:12964155

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000874 Streptomyces griseochromogenes
NCBITaxon:68214
CLUSTER_UNSTATED genbank:AY196214.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0000874MIBIG5
CHEBI:15353CHEBI3-star

This page is generated from data/natural_products/carbohydrates/blasticidin-s.yaml, which is generated from the committed inventories. Neither is edited by hand.