NaturalProductMech

o-orsellinate depside

CHEBI:15871 EXACT SEEDED

Structure

Standard InChIKeyHEMSJKZDHNSSEW-UHFFFAOYSA-N
SMILESCC1=CC(=CC(=C1C(=O)OC2=CC(=C(C(=C2)C)C(=O)O)O)O)O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA021170

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Claviceps purpurea 20.1
NCBITaxon:1111077
SOURCE_ASSERTION mibig:BGC0002596 PMID:33130255

Occurrences 25

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Dimelaena oreina
NCBITaxon:116793
LOTUS DOI:10.1080/00275514.1984.12023819
Dimelaena oreina
NCBITaxon:116793
LOTUS DOI:10.2307/3792846
Umbilicaria angulata
NCBITaxon:1217314
LOTUS DOI:10.1515/ZNC-1992-1-202
Ochrolechia parella
NCBITaxon:129506
LOTUS DOI:10.1021/NP060561P
Ochrolechia parella
NCBITaxon:129506
LOTUS DOI:10.1021/NP060561P.S001
Umbilicaria polyphylla
NCBITaxon:136372
LOTUS DOI:10.1515/ZNC-1992-1-202
Parmotrema nilgherrense
NCBITaxon:1450753
LOTUS DOI:10.1071/CH00137
Parmotrema grayanum
NCBITaxon:1566122
LOTUS DOI:10.3390/JOF9010116
Umbilicaria esculenta
NCBITaxon:161684
LOTUS DOI:10.1515/ZNC-1992-1-202
Umbilicaria mammulata
NCBITaxon:161685
LOTUS DOI:10.1515/ZNC-1992-1-202
Pseudocyphellaria crocata
NCBITaxon:161975
LOTUS DOI:10.1139/B75-121
Aspergillus nidulans
NCBITaxon:162425
LOTUS DOI:10.1073/PNAS.0901870106
Umbilicaria virginis
NCBITaxon:164626
LOTUS DOI:10.1515/ZNC-1992-1-202
Hypotrachyna horrescens
NCBITaxon:1709390
LOTUS DOI:10.1071/CH9762701
Parmelina tiliacea
NCBITaxon:172629
LOTUS DOI:10.2307/1218225
Punctelia borreri
NCBITaxon:172639
LOTUS DOI:10.2307/1218225
Umbilicaria freyi
NCBITaxon:1980225
LOTUS DOI:10.1515/ZNC-1992-1-202
Umbilicaria josiae
NCBITaxon:1980227
LOTUS DOI:10.1515/ZNC-1992-1-202
Parmotrema stuppeum
NCBITaxon:2041279
LOTUS DOI:10.1515/ZNC-2000-11-1227
Parmotrema stuppeum
NCBITaxon:2041279
LOTUS DOI:10.3390/JOF9010116
Umbilicaria proboscidea
NCBITaxon:232780
LOTUS DOI:10.1515/ZNC-1992-1-202
Parmelia cetrata
NCBITaxon:235861
LOTUS DOI:10.3390/JOF9010116
Parmotrema tinctorum
NCBITaxon:235862
LOTUS DOI:10.1002/J.1537-2197.1981.TB06359.X
Parmotrema tinctorum
NCBITaxon:235862
LOTUS DOI:10.1071/CH9762701
Parmotrema tinctorum
NCBITaxon:235862
LOTUS DOI:10.1093/CHROMSCI/36.1.8

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002596 Claviceps purpurea 20.1
NCBITaxon:1111077
CLUSTER_UNSTATED genbank:CAGA01000059.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

name-disagreement — ChEBI calls this structure 'o-orsellinate depside' and MIBiG calls it 'lecanoric acid'. They share a Standard InChIKey, so if the names denote different compounds then one upstream record has the wrong structure. Check which.

Provenance

Source conceptSourceVersion
BGC0002596MIBIG2
CHEBI:15871CHEBI3-star

This page is generated from data/natural_products/polyketides/o-orsellinate-depside.yaml, which is generated from the committed inventories. Neither is edited by hand.