NaturalProductMech

resistomycin

naturalproductmech:mibig-14d7cc15c5 MINTED SEEDED

Structure

Standard InChIKeyABLACSIRCKEUOB-UHFFFAOYSA-N
SMILESCC1=CC(=C2C3=C4C(=CC(=C13)O)C(C(=O)C5=C(C=C(C(=C45)C2=O)O)O)(C)C)O
Stereochemistryfully defined
Cross-referencespubchem:5282060

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces resistomycificus
NCBITaxon:67356
SOURCE_ASSERTION mibig:BGC0000264 PMID:14982421

Occurrences 16

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1002/CHIN.200412276
Streptomyces corchorusii
NCBITaxon:1903
LOTUS DOI:10.1134/S1068162006030125
Streptomyces olivaceoviridis
NCBITaxon:1921
LOTUS DOI:10.1134/S1068162006030125
Streptomyces vinaceus
NCBITaxon:1960
LOTUS DOI:10.1002/JLAC.198319830509
Streptomyces griseoincarnatus
NCBITaxon:29305
LOTUS DOI:10.7164/ANTIBIOTICS.38.113
Streptomyces griseoflavus
NCBITaxon:35619
LOTUS DOI:10.1002/JLAC.198319830509
Streptomyces aurantiacus
NCBITaxon:47760
LOTUS DOI:10.1007/S12275-011-1260-5
Streptomyces aurantiacus
NCBITaxon:47760
LOTUS DOI:10.1016/J.SAA.2011.12.072
Streptomyces canus
NCBITaxon:58343
LOTUS DOI:10.1021/JF305210U
Streptomyces variabilis
NCBITaxon:67372
LOTUS DOI:10.7164/ANTIBIOTICS.38.113
Streptomyces resistomycificus
NCBITaxon:67356
LOTUS DOI:10.1002/JLAC.198319830509
Streptomyces resistomycificus
NCBITaxon:67356
LOTUS DOI:10.1007/S13205-018-1304-1
Streptomyces resistomycificus
NCBITaxon:67356
LOTUS DOI:10.1016/J.FEBSLET.2009.07.061
Streptomyces resistomycificus
NCBITaxon:67356
LOTUS DOI:10.1016/J.SAA.2011.12.072
Streptomyces resistomycificus
NCBITaxon:67356
LOTUS DOI:10.1021/JA0390698
Streptomyces resistomycificus
NCBITaxon:67356
LOTUS DOI:10.1021/JO01284A072

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000264 Streptomyces resistomycificus
NCBITaxon:67356
CLUSTER_DEMONSTRATED genbank:AJ585192.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000264MIBIG5

This page is generated from data/natural_products/polyketides/resistomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.