NaturalProductMech

rimocidin

naturalproductmech:mibig-c5a4f915e6 MINTED SEEDED

Structure

Standard InChIKeyAWGBZRVEGDNLDZ-JCUCCFEFSA-N
SMILESCCC[C@@H]1C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](CCCC(=O)C[C@H]([C@@H](C(=O)O1)CC)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O
Stereochemistryfully defined
Cross-referencespubchem:6440843, npatlas:NPA020400

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces rimosus subsp. rimosus NRRL WC-3558
NCBITaxon:132474
BGC_CORRELATED mibig:BGC0002106 PMID:33057790
Streptomyces diastaticus
NCBITaxon:1956
SOURCE_ASSERTION mibig:BGC0000138 PMID:15123265

Occurrences 14

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces rimosus
NCBITaxon:1927
LOTUS DOI:10.1007/S10295-019-02146-W
Streptomyces rimosus
NCBITaxon:1927
LOTUS DOI:10.1016/J.JBIOSC.2012.07.020
Streptomyces rimosus
NCBITaxon:1927
LOTUS DOI:10.1111/JAM.13071
Streptomyces rimosus
NCBITaxon:1927
LOTUS DOI:10.1371/JOURNAL.PONE.0135891
Streptomyces rimosus
NCBITaxon:1927
LOTUS DOI:10.7164/ANTIBIOTICS.29.197
Streptomyces mauvecolor
NCBITaxon:58345
LOTUS DOI:10.1007/S10295-019-02146-W
Streptomyces mauvecolor
NCBITaxon:58345
LOTUS DOI:10.1016/J.JBIOSC.2012.07.020
Streptomyces mauvecolor
NCBITaxon:58345
LOTUS DOI:10.1111/JAM.13071
Streptomyces mauvecolor
NCBITaxon:58345
LOTUS DOI:10.1371/JOURNAL.PONE.0135891
Streptomyces diastaticus
NCBITaxon:1956
LOTUS DOI:10.1007/S10295-019-02146-W
Streptomyces diastaticus
NCBITaxon:1956
LOTUS DOI:10.1016/J.CHEMBIOL.2004.02.017
Streptomyces diastaticus
NCBITaxon:1956
LOTUS DOI:10.1016/J.JBIOSC.2012.07.020
Streptomyces diastaticus
NCBITaxon:1956
LOTUS DOI:10.1111/JAM.13071
Streptomyces diastaticus
NCBITaxon:1956
LOTUS DOI:10.1371/JOURNAL.PONE.0135891

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002106 Streptomyces rimosus subsp. rimosus NRRL WC-3558
NCBITaxon:132474
CLUSTER_CORRELATED genbank:NZ_JOBS01000013.1
mibig:BGC0000138 Streptomyces diastaticus
NCBITaxon:1956
CLUSTER_UNSTATED genbank:AY442225.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000138, BGC0002106. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002106MIBIG3
BGC0000138MIBIG5

This page is generated from data/natural_products/polyketides/rimocidin.yaml, which is generated from the committed inventories. Neither is edited by hand.