naringenin

CHEBI:50202 EXACT SEEDED cytotoxicenzyme inhibitor

What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 6 and 4'.

Structure

Standard InChIKey	FTVWIRXFELQLPI-UHFFFAOYSA-N
SMILES	C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O
Stereochemistry	undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-references	pubchem:932

Filing pathway

Shikimates and phenylpropanoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Streptomyces clavuligerus ATCC 27064 NCBITaxon:1901	SOURCE_ASSERTION	mibig:BGC0001310	PMID:26553209

Occurrences 25

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Prunus mume NCBITaxon:102107	LOTUS	DOI:10.1021/JF980936F
Helichrysum cephaloideum NCBITaxon:112358	LOTUS	DOI:10.1002/CBER.19731060432
Helichrysum cephaloideum NCBITaxon:112358	LOTUS	DOI:10.1515/ZNC-1983-11-1201
Dendrobium fimbriatum NCBITaxon:117953	LOTUS	DOI:10.1016/S0031-9422(01)00168-6
Dendrobium loddigesii NCBITaxon:117954	LOTUS	DOI:10.1016/S0031-9422(01)00168-6
Prunus lycioides NCBITaxon:1284230	LOTUS	DOI:10.3390/MOLECULES17021665
Dalbergia parviflora NCBITaxon:1353466	LOTUS	DOI:10.1039/P19730001737
Prunus campanulata NCBITaxon:136465	LOTUS	DOI:10.1021/JA01650A088
Rhynchosia beddomei NCBITaxon:1378005	LOTUS	DOI:10.1016/0031-9422(80)83211-0
Dendrobium moniliforme NCBITaxon:142614	LOTUS	DOI:10.1016/S0031-9422(01)00168-6
Dendrobium officinale NCBITaxon:142615	LOTUS	DOI:10.1155/2017/7436259
Prunus davidiana NCBITaxon:151430	LOTUS	DOI:10.1021/JF980936F
Dendrobium chrysanthum NCBITaxon:154291	LOTUS	DOI:10.1016/S0031-9422(01)00168-6
Dendrobium chrysotoxum NCBITaxon:161865	LOTUS	DOI:10.1016/S0031-9422(01)00168-6
Intsia NCBITaxon:162811	LOTUS	DOI:10.1016/0031-9422(73)80461-3
Brosimum acutifolium NCBITaxon:1835378	LOTUS	DOI:10.1021/NP010389J
Maclura cochinchinensis NCBITaxon:194324	LOTUS	DOI:10.1021/NP030127C
Maclura tricuspidata NCBITaxon:210328	LOTUS	DOI:10.1016/0031-9422(95)00277-E
Maclura tricuspidata NCBITaxon:210328	LOTUS	DOI:10.1021/NP030127C
Dendrobium longicornu NCBITaxon:257357	LOTUS	DOI:10.1055/S-2008-1074492
Dendrobium trigonopus NCBITaxon:257360	LOTUS	DOI:10.1080/10286020802133605
Helichrysum arenarium NCBITaxon:261776	LOTUS	DOI:10.1002/CBER.19731060432
Helichrysum arenarium NCBITaxon:261776	LOTUS	DOI:10.1515/ZNC-1983-11-1201
Ageratina havanensis NCBITaxon:2773069	LOTUS	DOI:10.1021/NP50048A063
Senecio adenophyllus NCBITaxon:2841764	LOTUS	DOI:10.1016/0031-9422(77)83033-1

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0001310	Streptomyces clavuligerus ATCC 27064 NCBITaxon:1901	CLUSTER_UNSTATED	genbank:CM000913.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

Causal graph — bioactivity 6 nodes, 5 edges

Naringenin inhibits human and bovine carbonic anhydrase isoenzymes.

Subject	Predicate	Object	Notes	Evidence
naringenin	inhibits	human carbonic anhydrase 1	PubChem BioAssay AID 1803217 maps this exact Standard InChIKey to a 0.97 uM Ki measurement against human carbonic anhydrase 1, and P00915 resolves in UniProtKB to the human CA1 gene product.	DOI:10.3109/14756366.2011.651464 reference DOI:10.3109/14756366.2011.651464 evidence type PRIMARY_EXPERIMENT notes The source article measured naringenin inhibition of alpha-carbonic anhydrase isoenzymes; the BindingDB-deposited PubChem assay reports active inhibition of human CA I.
naringenin	inhibits	human carbonic anhydrase 2	PubChem BioAssay AID 1803217 maps this exact Standard InChIKey to a 0.113 uM Ki measurement against human carbonic anhydrase 2, and P00918 resolves in UniProtKB to the human CA2 gene product.	DOI:10.3109/14756366.2011.651464 reference DOI:10.3109/14756366.2011.651464 evidence type PRIMARY_EXPERIMENT notes The source article measured naringenin inhibition of alpha-carbonic anhydrase isoenzymes; the BindingDB-deposited PubChem assay reports active inhibition of human CA II.
naringenin	inhibits	bovine carbonic anhydrase 3	PubChem BioAssay AID 1803217 maps this exact Standard InChIKey to a 2.21 uM Ki measurement against bovine carbonic anhydrase 3, and Q3SZX4 resolves in UniProtKB to the bovine CA3 gene product.	DOI:10.3109/14756366.2011.651464 reference DOI:10.3109/14756366.2011.651464 evidence type PRIMARY_EXPERIMENT notes The source article measured naringenin inhibition of alpha-carbonic anhydrase isoenzymes; the BindingDB-deposited PubChem assay reports active inhibition of bovine CA III.
naringenin	inhibits	human carbonic anhydrase 4	PubChem BioAssay AID 1803217 maps this exact Standard InChIKey to a 1.12 uM Ki measurement against human carbonic anhydrase 4, and P22748 resolves in UniProtKB to the human CA4 gene product.	DOI:10.3109/14756366.2011.651464 reference DOI:10.3109/14756366.2011.651464 evidence type PRIMARY_EXPERIMENT notes The source article measured naringenin inhibition of alpha-carbonic anhydrase isoenzymes; the BindingDB-deposited PubChem assay reports active inhibition of human CA IV.
naringenin	inhibits	human carbonic anhydrase 6	PubChem BioAssay AID 1803217 maps this exact Standard InChIKey to a 1.49 uM Ki measurement against human carbonic anhydrase 6, and P23280 resolves in UniProtKB to the human CA6 gene product.	DOI:10.3109/14756366.2011.651464 reference DOI:10.3109/14756366.2011.651464 evidence type PRIMARY_EXPERIMENT notes The source article measured naringenin inhibition of alpha-carbonic anhydrase isoenzymes; the BindingDB-deposited PubChem assay reports active inhibition of human CA VI.

Every edge carries its own citation; an uncited edge is refused by the corpus tests.

Causal graph — bioactivity 2 nodes, 1 edge

Naringenin inhibits human aromatase.

Subject	Predicate	Object	Notes	Evidence
naringenin	inhibits	human aromatase	BindingDB own-curated row 15 and BindingDB-deposited PubChem BioAssay AID 1799798 map this exact Standard InChIKey to an active, equal-qualified 0.00109662 nM Ki measurement against human aromatase; P11511 resolves in UniProtKB to the human CYP19A1 gene product.	DOI:10.1111/j.1747-0285.2012.01439.x reference DOI:10.1111/j.1747-0285.2012.01439.x evidence type PRIMARY_EXPERIMENT notes PMID:22726671 underlies the BindingDB/PubChem aromatase-inhibition measurement.

Every edge carries its own citation; an uncited edge is refused by the corpus tests.

Molecular targets 9

Target	Target organism	Measurement	Evidence
Aldehyde oxidase 1 PROTEIN BINDS UniProtKB:H9TB17	Cavia porcellus NCBITaxon:10141	KI 148000 nM	PMID:26722818 reference PMID:26722818 evidence type DATABASE_ASSERTION notes BindingDB own-curated affinity; measured at pH 7.0000; qualifier EQUAL.
Aromatase PROTEIN BINDS UniProtKB:P11511	Homo sapiens NCBITaxon:9606	KI 0.00109662 nM	PMID:22726671 reference PMID:22726671 evidence type DATABASE_ASSERTION notes BindingDB own-curated affinity; qualifier EQUAL.
Carbonic anhydrase 1 PROTEIN BINDS UniProtKB:P00915	Homo sapiens NCBITaxon:9606	KI 970 nM	PMID:22299585 reference PMID:22299585 evidence type DATABASE_ASSERTION notes BindingDB own-curated affinity; measured at pH 7.4000; qualifier EQUAL.
Carbonic anhydrase 2 PROTEIN BINDS UniProtKB:P00918	Homo sapiens NCBITaxon:9606	KI 113 nM	PMID:22299585 reference PMID:22299585 evidence type DATABASE_ASSERTION notes BindingDB own-curated affinity; measured at pH 7.4000; qualifier EQUAL.
Carbonic anhydrase 3 PROTEIN BINDS UniProtKB:Q3SZX4	Bos taurus NCBITaxon:9913	KI 2210 nM	PMID:22299585 reference PMID:22299585 evidence type DATABASE_ASSERTION notes BindingDB own-curated affinity; measured at pH 7.4000; qualifier EQUAL.
Carbonic anhydrase 4 PROTEIN BINDS UniProtKB:P22748	Homo sapiens NCBITaxon:9606	KI 1120 nM	PMID:22299585 reference PMID:22299585 evidence type DATABASE_ASSERTION notes BindingDB own-curated affinity; measured at pH 7.4000; qualifier EQUAL.
Carbonic anhydrase 6 PROTEIN BINDS UniProtKB:P23280	Homo sapiens NCBITaxon:9606	KI 1490 nM	PMID:22299585 reference PMID:22299585 evidence type DATABASE_ASSERTION notes BindingDB own-curated affinity; measured at pH 7.4000; qualifier EQUAL.
Estrogen receptor PROTEIN BINDS UniProtKB:P03372	Homo sapiens NCBITaxon:9606	IC50 72302 nM	PMID:17149865 reference PMID:17149865 evidence type DATABASE_ASSERTION notes BindingDB own-curated affinity; measured at pH 7.6000, 22.00 C C; qualifier EQUAL.
Estrogen receptor beta PROTEIN BINDS UniProtKB:Q92731	Homo sapiens NCBITaxon:9606	IC50 13473 nM	PMID:17149865 reference PMID:17149865 evidence type DATABASE_ASSERTION notes BindingDB own-curated affinity; measured at pH 7.6000, 22.00 C C; qualifier EQUAL.

Bioactivities 25

Entries preserve source qualifiers, targets and evidence. Repeated assay names or values are not independent replications; inspect source detail for differences.

Explore across X-Mech

AntibioticMech (naringenin) ↗ MediaIngredientMech (CHEBI:50202) ↗ TaxonMech: Streptomyces clavuligerus ATCC 27064 (NCBITaxon:1901) ↗ PathwayMech (mibig:BGC0001310) ↗

Provenance

Source concept	Source	Version
BGC0001310	MIBIG	5
CHEBI:50202	CHEBI	3-star

This page is generated from data/natural_products/shikimates_and_phenylpropanoids/naringenin.yaml, which is generated from the committed inventories. Neither is edited by hand.

Assay	Result	Target enzyme	Source detail
A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells.	OTHER 2.5119 uM; INACTIVE	Not recorded	pubchem.aid:624297 assay A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. evidence reference pubchem.aid:624297 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 624297, deposited by NCGC; assay type Confirmatory. Source endpoint: Potency. Target accession NP_056979 was left ungrounded because PubChem did not provide a UniProtKB accession. call INACTIVE measurement type OTHER value 2.5119 units uM
AO Enzyme Assay from Article 10.1016/j.bioorg.2015.12.004: "Inhibition of guinea pig aldehyde oxidase activity by different flavonoid compounds: An in vitro study."	KI 148 uM; INACTIVE	UniProtKB:H9TB17	PMID:26722818 assay AO Enzyme Assay from Article 10.1016/j.bioorg.2015.12.004: "Inhibition of guinea pig aldehyde oxidase activity by different flavonoid compounds: An in vitro study." evidence reference PMID:26722818 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1801531, deposited by BindingDB; assay type Confirmatory. call INACTIVE measurement type KI value 148.0 units uM target enzyme UniProtKB:H9TB17
Aromatase Assay from Article 10.1111/j.1747-0285.2012.01439.x: "Neoflavonoids and Tetrahydroquinolones as Possible Cancer Chemopreventive Agents."	KI 1.09662e-06 uM; ACTIVE	UniProtKB:P11511	PMID:22726671 assay Aromatase Assay from Article 10.1111/j.1747-0285.2012.01439.x: "Neoflavonoids and Tetrahydroquinolones as Possible Cancer Chemopreventive Agents." evidence reference PMID:22726671 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1799798, deposited by BindingDB; assay type Confirmatory. call ACTIVE measurement type KI value 1.09662e-06 units uM target enzyme UniProtKB:P11511 activity class CYTOTOXIC
Competition-Based Ligand Binding Assay. from Article 10.1021/jm060692n: "Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta."	IC50 72.302 uM; INACTIVE	UniProtKB:P03372	PMID:17149865 assay Competition-Based Ligand Binding Assay. from Article 10.1021/jm060692n: "Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta." evidence reference PMID:17149865 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1797856, deposited by BindingDB; assay type Confirmatory. call INACTIVE measurement type IC50 value 72.302 units uM target enzyme UniProtKB:P03372
Competition-Based Ligand Binding Assay. from Article 10.1021/jm060692n: "Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta."	IC50 13.473 uM; INACTIVE	UniProtKB:Q92731	PMID:17149865 assay Competition-Based Ligand Binding Assay. from Article 10.1021/jm060692n: "Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta." evidence reference PMID:17149865 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1797856, deposited by BindingDB; assay type Confirmatory. call INACTIVE measurement type IC50 value 13.473 units uM target enzyme UniProtKB:Q92731
Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes."	KI 0.97 uM; ACTIVE	UniProtKB:P00915	PMID:22299585 assay Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes." evidence reference PMID:22299585 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1803217, deposited by BindingDB; assay type Confirmatory. call ACTIVE measurement type KI value 0.97 units uM target enzyme UniProtKB:P00915 activity class ENZYME_INHIBITOR
Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes."	KI 0.113 uM; ACTIVE	UniProtKB:P00918	PMID:22299585 assay Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes." evidence reference PMID:22299585 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1803217, deposited by BindingDB; assay type Confirmatory. call ACTIVE measurement type KI value 0.113 units uM target enzyme UniProtKB:P00918 activity class ENZYME_INHIBITOR
Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes."	KI 1.12 uM; ACTIVE	UniProtKB:P22748	PMID:22299585 assay Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes." evidence reference PMID:22299585 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1803217, deposited by BindingDB; assay type Confirmatory. call ACTIVE measurement type KI value 1.12 units uM target enzyme UniProtKB:P22748 activity class ENZYME_INHIBITOR
Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes."	KI 1.49 uM; ACTIVE	UniProtKB:P23280	PMID:22299585 assay Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes." evidence reference PMID:22299585 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1803217, deposited by BindingDB; assay type Confirmatory. call ACTIVE measurement type KI value 1.49 units uM target enzyme UniProtKB:P23280 activity class ENZYME_INHIBITOR
Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes."	KI 2.21 uM; ACTIVE	UniProtKB:Q3SZX4	PMID:22299585 assay Esterase Activity Assay from Article 10.3109/14756366.2011.651464: "Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes." evidence reference PMID:22299585 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1803217, deposited by BindingDB; assay type Confirmatory. call ACTIVE measurement type KI value 2.21 units uM target enzyme UniProtKB:Q3SZX4 activity class ENZYME_INHIBITOR
High Throughput Screening for Foot and Mouth Disease Virus Antivirals	OTHER 14.1254 uM; INACTIVE	Not recorded	pubchem.aid:1159524 assay High Throughput Screening for Foot and Mouth Disease Virus Antivirals evidence reference pubchem.aid:1159524 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1159524, deposited by NCGC; assay type Confirmatory. Source endpoint: Potency. call INACTIVE measurement type OTHER value 14.1254 units uM
Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2	OTHER 44.6684 uM; NOT_DETERMINED	Not recorded	pubchem.aid:1671190 assay Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2 evidence reference pubchem.aid:1671190 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1671190, deposited by NCGC; assay type Confirmatory. Source outcome: Inconclusive. Source endpoint: Potency. call NOT_DETERMINED measurement type OTHER value 44.6684 units uM
Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2	OTHER 44.6684 uM; NOT_DETERMINED	UniProtKB:P18054	pubchem.aid:1671190 assay Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2 evidence reference pubchem.aid:1671190 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1671190, deposited by NCGC; assay type Confirmatory. Source outcome: Inconclusive. Source endpoint: Potency. call NOT_DETERMINED measurement type OTHER value 44.6684 units uM target enzyme UniProtKB:P18054
Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation	OTHER 2.6169 uM; INACTIVE	Not recorded	pubchem.aid:504832 assay Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation evidence reference pubchem.aid:504832 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 504832, deposited by NCGC; assay type Confirmatory. Source endpoint: Potency. call INACTIVE measurement type OTHER value 2.6169 units uM
Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation	OTHER 6.5733 uM; INACTIVE	Not recorded	pubchem.aid:504834 assay Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation evidence reference pubchem.aid:504834 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 504834, deposited by NCGC; assay type Confirmatory. Source endpoint: Potency. call INACTIVE measurement type OTHER value 6.5733 units uM
qHTS Assay for Activators of Cytochrome P450 3A4	OTHER 10 uM; INACTIVE	Not recorded	pubchem.aid:885 assay qHTS Assay for Activators of Cytochrome P450 3A4 evidence reference pubchem.aid:885 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 885, deposited by NCGC; assay type Confirmatory. Source endpoint: Potency. Target accession NP_059488 was left ungrounded because PubChem did not provide a UniProtKB accession. call INACTIVE measurement type OTHER value 10.0 units uM
qHTS Assay for Activators of Cytochrome P450 3A4	OTHER 12.5893 uM; INACTIVE	Not recorded	pubchem.aid:885 assay qHTS Assay for Activators of Cytochrome P450 3A4 evidence reference pubchem.aid:885 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 885, deposited by NCGC; assay type Confirmatory. Source endpoint: Potency. Target accession NP_059488 was left ungrounded because PubChem did not provide a UniProtKB accession. call INACTIVE measurement type OTHER value 12.5893 units uM
qHTS Assay for Compounds that Induce Erasure of Genomic Imprints	OTHER 12.5893 uM; INACTIVE	Not recorded	pubchem.aid:1948 assay qHTS Assay for Compounds that Induce Erasure of Genomic Imprints evidence reference pubchem.aid:1948 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1948, deposited by NCGC; assay type Confirmatory. Source endpoint: Potency. call INACTIVE measurement type OTHER value 12.5893 units uM
qHTS Assay for Compounds that Induce Erasure of Genomic Imprints	OTHER 15.8489 uM; INACTIVE	Not recorded	pubchem.aid:1948 assay qHTS Assay for Compounds that Induce Erasure of Genomic Imprints evidence reference pubchem.aid:1948 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1948, deposited by NCGC; assay type Confirmatory. Source endpoint: Potency. call INACTIVE measurement type OTHER value 15.8489 units uM
qHTS Assay for Identification of Novel General Anesthetics	OTHER 28.1838 uM; NOT_DETERMINED	Not recorded	pubchem.aid:485281 assay qHTS Assay for Identification of Novel General Anesthetics evidence reference pubchem.aid:485281 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 485281, deposited by NCGC; assay type Confirmatory. Source outcome: Inconclusive. Source endpoint: Potency. Target accession 3F32_A was left ungrounded because PubChem did not provide a UniProtKB accession. call NOT_DETERMINED measurement type OTHER value 28.1838 units uM
qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide	OTHER 25.1189 uM; NOT_DETERMINED	Not recorded	pubchem.aid:1768 assay qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide evidence reference pubchem.aid:1768 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1768, deposited by NCGC; assay type Confirmatory. Source outcome: Inconclusive. Source endpoint: Potency. Target accession NP_000235 was left ungrounded because PubChem did not provide a UniProtKB accession. call NOT_DETERMINED measurement type OTHER value 25.1189 units uM
qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide	OTHER 25.1189 uM; NOT_DETERMINED	Not recorded	pubchem.aid:1768 assay qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide evidence reference pubchem.aid:1768 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1768, deposited by NCGC; assay type Confirmatory. Source outcome: Inconclusive. Source endpoint: Potency. Target accession NP_005924 was left ungrounded because PubChem did not provide a UniProtKB accession. call NOT_DETERMINED measurement type OTHER value 25.1189 units uM
qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide	OTHER 39.8107 uM; NOT_DETERMINED	Not recorded	pubchem.aid:1768 assay qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide evidence reference pubchem.aid:1768 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1768, deposited by NCGC; assay type Confirmatory. Source outcome: Inconclusive. Source endpoint: Potency. Target accession NP_000235 was left ungrounded because PubChem did not provide a UniProtKB accession. call NOT_DETERMINED measurement type OTHER value 39.8107 units uM
qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide	OTHER 39.8107 uM; NOT_DETERMINED	Not recorded	pubchem.aid:1768 assay qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide evidence reference pubchem.aid:1768 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1768, deposited by NCGC; assay type Confirmatory. Source outcome: Inconclusive. Source endpoint: Potency. Target accession NP_005924 was left ungrounded because PubChem did not provide a UniProtKB accession. call NOT_DETERMINED measurement type OTHER value 39.8107 units uM
qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease	OTHER 11.2202 uM; NOT_DETERMINED	Not recorded	pubchem.aid:2101 assay qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease evidence reference pubchem.aid:2101 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 2101, deposited by NCGC; assay type Confirmatory. Source outcome: Inconclusive. Source endpoint: Potency. Target accession BAA02545 was left ungrounded because PubChem did not provide a UniProtKB accession. call NOT_DETERMINED measurement type OTHER value 11.2202 units uM notes 19 further PubChem assay results are in data/raw/pubchem_bioassay.tsv but not written here.