biscognienyne B
CHEBI:167050 EXACT SEEDED
A member of the class of epoxides that is (1R,6S)-7-oxabicyclo[4.1.0]hept-3-ene substituted by 3-methylbut-2-en-1-yl, hydroxy, 2-methylbut-1-en-3-yn-4-yl, and hydroxy groups at positions 1, 2R, 3 and 5R. It is a meroterpenoid natural product synthesized by the Ascomycota fungus Biscogniauxia sp.
Structure
| Standard InChIKey | UAAPCPSYCUMTPM-LVQVYYBASA-N |
|---|---|
| SMILES | CC(=CC[C@@]12[C@@H](O1)[C@@H](C=C([C@H]2O)C#CC(=C)C)O)C |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA023808 |
Filing pathway
Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Biscogniauxia sp. NCBITaxon:1896107 |
SOURCE_ASSERTION | mibig:BGC0002290 | PMID:32364293 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Biscogniauxia NCBITaxon:97376 |
LOTUS | DOI:10.1021/ACS.ORGLETT.6B03264 |
| Biscogniauxia sp. NCBITaxon:1896107 |
CHEBI | PMID:32364293 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002290 | Biscogniauxia sp. NCBITaxon:1896107 |
CLUSTER_DEMONSTRATED | genbank:MT109335.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002290 | MIBIG | 2 |
| CHEBI:167050 | CHEBI | 3-star |
This page is generated from data/natural_products/terpenoids/biscognienyne-b.yaml, which is generated from the committed inventories. Neither is edited by hand.