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euphol

naturalproductmech:mibig-21e4f2495f MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.
What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKeyCAHGCLMLTWQZNJ-WZLOIPHISA-N
SMILESC[C@H](CCC=C(C)C)[C@@H]1CC[C@]2([C@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C
Stereochemistryfully defined
Cross-referencespubchem:441678, CHEBI:4940

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Arabidopsis thaliana
NCBITaxon:3702		 BGC_CHARACTERIZED mibig:BGC0002401 DOI:10.1111/nph.16338

Occurrences 25

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Euphorbia nicaeensis
NCBITaxon:1087772		 LOTUS DOI:10.1055/S-2006-959736
Euphorbia boetica
NCBITaxon:1091613		 LOTUS DOI:10.1021/NP50116A020
Euphorbia oxyphylla
NCBITaxon:1091639		 LOTUS DOI:10.1016/S0031-9422(00)82286-4
Euphorbia retusa
NCBITaxon:1091645		 LOTUS DOI:10.1016/0031-9422(73)80529-1
Euphorbia sulcata
NCBITaxon:1091647		 LOTUS DOI:10.1016/0031-9422(73)80529-1
Euphorbia caducifolia
NCBITaxon:1129975		 LOTUS DOI:10.1016/S0031-9422(00)97902-0
Euphorbia portulacoides
NCBITaxon:1138358		 LOTUS DOI:10.1016/0031-9422(95)00752-0
Euphorbia sapinii
NCBITaxon:1281384		 LOTUS DOI:10.1016/J.PHYTOL.2011.04.001
Euphorbia aleppica
NCBITaxon:1333886		 LOTUS DOI:10.1016/0031-9422(95)00361-A
Euphorbia tirucalli
NCBITaxon:142860		 LOTUS DOI:10.1021/NP50006A011
Euphorbia tirucalli
NCBITaxon:142860		 LOTUS DOI:10.1515/ZNC-1985-9-1008
Euphorbia trigona
NCBITaxon:1492770		 LOTUS DOI:10.1016/0031-9422(88)83136-4
Clusia multiflora
NCBITaxon:156472		 LOTUS DOI:10.1016/0031-9422(94)00642-7
Dacryodes hopkinsii
NCBITaxon:1591303		 LOTUS DOI:10.1590/S0103-50532004000300008
Camellia sasanqua
NCBITaxon:182300		 LOTUS DOI:10.1021/NP970490H
Camellia sasanqua
NCBITaxon:182300		 LOTUS DOI:10.1248/CPB.45.2016
Garcinia cymosa
NCBITaxon:198793		 LOTUS DOI:10.1016/S0031-9422(98)00565-2
Garcinia cymosa
NCBITaxon:198793		 LOTUS DOI:10.1080/14786419.2012.725399
Clusia columnaris
NCBITaxon:211701		 LOTUS DOI:10.1590/S0102-695X2008000100003
Euphorbia drupifera
NCBITaxon:212879		 LOTUS DOI:10.1016/J.FITOTE.2007.02.002
Euphorbia lathyris
NCBITaxon:212925		 LOTUS DOI:10.1104/PP.89.2.681
Euphorbia lathyris
NCBITaxon:212925		 LOTUS DOI:10.3390/MOLECULES24234322
Euphorbia kansui
NCBITaxon:239687		 LOTUS DOI:10.1021/NP0205396
Euphorbia kansui
NCBITaxon:239687		 LOTUS DOI:10.1055/S-2006-957574
Euphorbia kansui
NCBITaxon:239687		 LOTUS DOI:10.1211/0022357001773607

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002401 Arabidopsis thaliana
NCBITaxon:3702 		CLUSTER_DEMONSTRATED genbank:CP002686.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

PRODUCERS & OCCURRENCE 1 producer (1 causal) 25 cited occurrences BIOSYNTHETIC LOCUS 1 gene cluster 0 curated pathway steps NATURAL PRODUCT euphol naturalproductmech:mibig-21e4f2495f Terpenoids TARGETS & BIOACTIVITY 0 molecular targets 0 bioactivities · 0 graphs

Explore across X-Mech

AntibioticMech (euphol) ↗ MediaIngredientMech (naturalproductmech:mibig-21e4f2495f) ↗ TaxonMech: Arabidopsis thaliana (NCBITaxon:3702) ↗ PathwayMech (mibig:BGC0002401) ↗

Provenance

Source conceptSourceVersion
BGC0002401MIBIG2

This page is generated from data/natural_products/terpenoids/euphol.yaml, which is generated from the committed inventories. Neither is edited by hand.