5-bromo-8-methoxy-1-methyl-β-carboline

CHEBI:65524 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A member of the class of β-carboline that is 9H-β-carboline substituted by bromo, methoxy and a methyl group at positions 5, 8 and 1 respectively. It is isolated from a marine bryozoan Pterocella vesiculosa and has been found to exhibit moderate antitumour activity against the P388 murine leukemia cell line. Additionally it shows antimicrobial activity towards the Gram-positive bacterium Bacillus subtilis and the fungi Candida albicans and Trichophyton mentagrophytes. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:22315 CHEBI:22315
CHEBI:35618 CHEBI:35618
CHEBI:37141 CHEBI:37141
CHEBI:60834 CHEBI:60834

Chemical structure

Computed structure properties
Molecular formula	C13H11BrN2O
Charge	0
Average mass	291.148 Da
Monoisotopic mass	290.00548 Da
Source	ChEBI
InChIKey	OVNRKQHNHZRXHF-UHFFFAOYSA-N

SMILES

COc1ccc(Br)c2c1nc1c(C)nccc12

InChI

InChI=1S/C13H11BrN2O/c1-7-12-8(5-6-15-7)11-9(14)3-4-10(17-2)13(11)16-12/h3-6,16H,1-2H3

Also called

5-bromo-8-methoxy-1-methyl-9H-β-carboline (EXACT_SYNONYM)— chebi

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33282 CHEBI:33282
CHEBI:35718 CHEBI:35718

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:65524`	5-bromo-8-methoxy-1-methyl-β-carboline	`antibioticmech:chebi-16255b92a3`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.