6'-N-ethylnetilmicin

antibioticmech:aro-e4e652725f ·ANTIBACTERIAL ·MINTED SEEDED

6'-N-ethylnetilmicin is an aminoglycoside antibiotic and a derivative of netilmicin. — PMID:8385262

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

aminoglycoside antibioticARO:0000016

Strictly broader compounds or drug classes this molecule belongs to.

aminoglycoside antibiotic ARO:0000016

Chemical structure

Computed structure properties
Molecular formula	C23H45N5O7
Charge	0
Average mass	503.6 Da
Monoisotopic mass	503.33189879 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	RZXCDENQJDMFQY-OLUUFXIRSA-N

SMILES

CCNCC1=CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)NCC)N)N

InChI

InChI=1S/C23H45N5O7/c1-5-27-10-12-7-8-13(24)21(33-12)34-18-14(25)9-15(28-6-2)19(16(18)29)35-22-17(30)20(26-4)23(3,31)11-32-22/h7,13-22,26-31H,5-6,8-11,24-25H2,1-4H3/t13-,14+,15-,16+,17-,18-,19+,20-,21-,22-,23+/m1/s1

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

6'-N-ethylnetilmicinARO:3007377
pubchem.compound:15344654

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3007377`	6'-N-ethylnetilmicin	`antibioticmech:aro-e4e652725f`	2026-08-30

Resistance mechanisms

13 source-backed resistance determinants or associations, with ARO grounding where reported. Grouped by reported mechanism type.

ANTIBIOTIC_INACTIVATION 13

ANTIBIOTIC_INACTIVATION
Determinant	ARO ID	Organism	Gene families	Evidence
AAC(2')-Ia	ARO:3002523	not organism-specific	—	ARO:3002523 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(2')-Ib	ARO:3002524	not organism-specific	—	ARO:3002524 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(2')-Ic	ARO:3002525	not organism-specific	—	ARO:3002525 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(2')-Id	ARO:3002526	not organism-specific	—	ARO:3002526 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(2')-Ie	ARO:3002527	not organism-specific	—	ARO:3002527 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(3)-IIa	ARO:3002533	not organism-specific	—	ARO:3002533 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(3)-IIb	ARO:3002534	not organism-specific	—	ARO:3002534 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(3)-IIc	ARO:3002535	not organism-specific	—	ARO:3002535 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(3)-IId	ARO:3004623	not organism-specific	—	ARO:3004623 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(3)-IIe	ARO:3004621	not organism-specific	—	ARO:3004621 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(3)-IIg	ARO:3005085	not organism-specific	—	ARO:3005085 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(3)-IVa	ARO:3002539	not organism-specific	—	ARO:3002539 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)
AAC(3)-VIa	ARO:3002540	not organism-specific	—	ARO:3002540 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007377 (6'-N-ethylnetilmicin); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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