alexidine

CHEBI:53661 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:53662 CHEBI:53662

Chemical structure

Computed structure properties
Molecular formula	C26H56N10
Charge	0
Average mass	508.804 Da
Monoisotopic mass	508.46894 Da
Source	ChEBI
InChIKey	LFVVNPBBFUSSHL-UHFFFAOYSA-N

SMILES

CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC

InChI

InChI=1S/C26H56N10/c1-5-9-15-21(7-3)19-33-25(29)35-23(27)31-17-13-11-12-14-18-32-24(28)36-26(30)34-20-22(8-4)16-10-6-2/h21-22H,5-20H2,1-4H3,(H5,27,29,31,33,35)(H5,28,30,32,34,36)

Also called

alexidina (INN)— chebi
alexidinum (INN)— chebi
N,N''''-hexane-1,6-diylbis[N'-(2-ethylhexyl)(imidodicarbonimidic diamide)] (EXACT_SYNONYM)— chebi
1,1'-Hexamethylenebis(5-(2-ethylhexyl)biguanide) (EXACT_SYNONYM)— chebi
N,N'-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide (EXACT_SYNONYM)— chebi
bisguadine (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:22573-93-9
drugcentral:113
lincs.smallmolecule:LSM-4432
patent:CN101624356
reaxys:2404807
wikipedia.en:Alexidine

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33282 CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:53661`	alexidine	`antibioticmech:chebi-275124c3cb`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.