antibiotic A40926

antibioticmech:aro-59d21b914e ·ANTIBACTERIAL ·MINTED SEEDED

A40926 is a glycopeptide antibiotic produced by Nonomuraea sp. ATCC 39727. It is precusor of the second-generation glycopeptide antibiotic dalbavancin. — PMID:12837387

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

glycopeptide antibioticARO:3000081

Strictly broader compounds or drug classes this molecule belongs to.

ARO:3000081 ARO:3000081

Chemical structure

Computed structure properties
Molecular formula	C71H66Cl2N8O28
Charge	0
Average mass	1550.2 Da
Monoisotopic mass	1548.3363589 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	VZDDQLYACFXSQP-KBQMXOHMSA-N

SMILES

CN[C@@H]1C2=CC(=C(C=C2)O)OC3=CC(=C(C(=C3)O)Cl)[C@H]4C(=O)N[C@@H]5C6=CC(=C(C(=C6)OC7=C(C=C(C=C7)[C@H]([C@H]8C(=O)N[C@@H](C9=C(C(=CC(=C9)O)O[C@@H]2[C@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)C2=C(C=CC(=C2)[C@H](C(=O)N8)NC5=O)O)C(=O)O)O)Cl)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O)O)N)OC2=CC=C(C[C@H](C(=O)N4)NC1=O)C=C2

InChI

InChI=1S/C71H66Cl2N8O28/c1-75-48-25-5-10-37(85)40(15-25)104-30-20-33(46(73)38(86)21-30)51-66(97)78-50-27-16-42(103-29-7-2-23(3-8-29)12-35(62(93)79-51)76-63(48)94)60(108-70-47(74)56(89)58(91)61(109-70)69(101)102)43(17-27)105-39-11-6-26(14-34(39)72)54(87)53-67(98)80-52(68(99)100)32-18-28(83)19-41(106-71-59(92)57(90)55(88)44(22-82)107-71)45(32)31-13-24(4-9-36(31)84)49(64(95)81-53)77-65(50)96/h2-11,13-21,35,44,47-59,61,70-71,75,82-92H,12,22,74H2,1H3,(H,76,94)(H,77,96)(H,78,97)(H,79,93)(H,80,98)(H,81,95)(H,99,100)(H,101,102)/t35-,44-,47-,48-,49-,50-,51+,52+,53+,54-,55-,56-,57+,58+,59+,61+,70-,71+/m1/s1

Cross-references

Equivalent identifiers for this same structure in other resources.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3000525`	antibiotic A40926	`antibioticmech:aro-59d21b914e`	2026-08-30

Molecular targets

The molecular entity or process this compound acts on. Each target carries evidence — this is a mechanistic claim, not a classification.

acyl-D-alanyl-D-alanine CELL_WALL_COMPONENT ATTACKED_COMPONENT

ARO:3000720

CARD/ARO database assertion; target organism, strain, and assay are not specified. The D-Ala-D-Ala chemical group is bound as a cell-wall precursor component. Evidence status: DATABASE_ASSERTION_ONLY. Source: CARD_ARO 2026-08-30 (retrieved 2026-08-30).

ARO:3000720 (CARD/ARO asserts targeted_by_antibiotic ARO:3000525 (antibiotic A40926); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.