antibiotic A40926

antibioticmech:aro-59d21b914e ·ANTIBACTERIAL ·MINTED SEEDED

A40926 is a glycopeptide antibiotic produced by Nonomuraea sp. ATCC 39727. It is precusor of the second-generation glycopeptide antibiotic dalbavancin. — PMID:12837387

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

glycopeptide antibioticARO:3000081

Strictly broader compounds or drug classes this molecule belongs to.

glycopeptide antibiotic ARO:3000081

Chemical structure

Computed structure properties
Molecular formula	C71H66Cl2N8O28
Charge	0
Average mass	1550.2 Da
Monoisotopic mass	1548.3363589 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	VZDDQLYACFXSQP-KBQMXOHMSA-N

SMILES

CN[C@@H]1C2=CC(=C(C=C2)O)OC3=CC(=C(C(=C3)O)Cl)[C@H]4C(=O)N[C@@H]5C6=CC(=C(C(=C6)OC7=C(C=C(C=C7)[C@H]([C@H]8C(=O)N[C@@H](C9=C(C(=CC(=C9)O)O[C@@H]2[C@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)C2=C(C=CC(=C2)[C@H](C(=O)N8)NC5=O)O)C(=O)O)O)Cl)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O)O)N)OC2=CC=C(C[C@H](C(=O)N4)NC1=O)C=C2

InChI

InChI=1S/C71H66Cl2N8O28/c1-75-48-25-5-10-37(85)40(15-25)104-30-20-33(46(73)38(86)21-30)51-66(97)78-50-27-16-42(103-29-7-2-23(3-8-29)12-35(62(93)79-51)76-63(48)94)60(108-70-47(74)56(89)58(91)61(109-70)69(101)102)43(17-27)105-39-11-6-26(14-34(39)72)54(87)53-67(98)80-52(68(99)100)32-18-28(83)19-41(106-71-59(92)57(90)55(88)44(22-82)107-71)45(32)31-13-24(4-9-36(31)84)49(64(95)81-53)77-65(50)96/h2-11,13-21,35,44,47-59,61,70-71,75,82-92H,12,22,74H2,1H3,(H,76,94)(H,77,96)(H,78,97)(H,79,93)(H,80,98)(H,81,95)(H,99,100)(H,101,102)/t35-,44-,47-,48-,49-,50-,51+,52+,53+,54-,55-,56-,57+,58+,59+,61+,70-,71+/m1/s1

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3000525`	antibiotic A40926	`antibioticmech:aro-59d21b914e`	2026-08-30

Molecular targets

The molecular entity or process this compound acts on. Each target carries evidence — this is a mechanistic claim, not a classification.

acyl-D-alanyl-D-alanine CELL_WALL_COMPONENT ATTACKED_COMPONENT

ARO:3000720

CARD/ARO database assertion; target organism, strain, and assay are not specified. The D-Ala-D-Ala chemical group is bound as a cell-wall precursor component. Evidence status: DATABASE_ASSERTION_ONLY. Source: CARD_ARO 2026-08-30 (retrieved 2026-08-30).

ARO:3000720 (CARD/ARO asserts targeted_by_antibiotic ARO:3000525 (antibiotic A40926); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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