AntibioticMech

arsinothricin

antibioticmech:aro-d03e1e5b82 ·ANTIBACTERIAL ·MINTED SEEDED

Arsinothricin is a natural product synthesized by the rhizosphere bacterium Burkholderia gladioli GSRB05 and is a broad-spectrum antibiotic effective against human pathogens such as carbapenem-resistant Enterobacter cloacae. It is a non-proteogenic amino acid and glutamate mimetic that inhibits bacterial glutamine synthetase. — PMID:36785875

Classification

organoarsenic antibioticARO:3000551

Strictly broader compounds or drug classes this molecule belongs to.

• ARO:3000551 ARO:3000551

Chemical structure

Computed structure properties

Molecular formula	C5H12AsNO4
Charge	0
Average mass	225.07 Da
Monoisotopic mass	224.998227 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	CXTQPLOKUBDLTK-UHFFFAOYSA-N

SMILES

C[As](=O)(CCC(C(=O)O)N)O

InChI

InChI=1S/C5H12AsNO4/c1-6(10,11)3-2-4(7)5(8)9/h4H,2-3,7H2,1H3,(H,8,9)(H,10,11)

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3007534
• CHEBI:220158
• pubchem.compound:170988177

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3007534	arsinothricin	antibioticmech:aro-d03e1e5b82	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.