AntibioticMech

carbomycin

antibioticmech:aro-27630f7c54 ·ANTIBACTERIAL ·MINTED SEEDED

Produced by Streptomyces halstedii and Streptomyces thermotolerans. — PMID:24542077

Classification

macrolide antibioticARO:0000000

Strictly broader compounds or drug classes this molecule belongs to.

• ARO:0000000 ARO:0000000

Chemical structure

Computed structure properties

Molecular formula	C42H67NO16
Charge	0
Average mass	842.0 Da
Monoisotopic mass	841.44598505 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	FQVHOULQCKDUCY-OGHXVOSASA-N

SMILES

C[C@@H]1C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O[C@@H](C[C@H]2[C@@H](O2)/C=C/C1=O)C)OC(=O)C)OC)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C)O[C@H]4C[C@@]([C@H]([C@@H](O4)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O

InChI

InChI=1S/C42H67NO16/c1-21(2)16-32(47)57-40-25(6)53-34(20-42(40,8)50)58-37-24(5)54-41(36(49)35(37)43(9)10)59-38-27(14-15-44)17-22(3)28(46)12-13-29-30(56-29)18-23(4)52-33(48)19-31(39(38)51-11)55-26(7)45/h12-13,15,21-25,27,29-31,34-41,49-50H,14,16-20H2,1-11H3/b13-12+/t22-,23-,24-,25+,27+,29+,30+,31-,34+,35-,36-,37-,38+,39+,40+,41+,42-/m1/s1

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3001228
• chembl:CHEMBL3989435
• pubchem.compound:5287879

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3001228	carbomycin	antibioticmech:aro-27630f7c54	2026-08-30

Resistance mechanisms

5 known routes by which microbes resist this compound, grounded in ARO where CARD models them. Grouped by mechanism type — expand a group to see its determinants.

ANTIBIOTIC_TARGET_ALTERATION 4

ANTIBIOTIC_TARGET_ALTERATION

Determinant	ARO ID	Organism	Gene families	Evidence
ErmH	ARO:3002823	not organism-specific	—	ARO:3002823 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)
ErmO-srmA	ARO:3001303	not organism-specific	—	ARO:3001303 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)
ErmS	ARO:3001304	not organism-specific	—	ARO:3001304 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)
ErmV	ARO:3002824	not organism-specific	—	ARO:3002824 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)

ANTIBIOTIC_TARGET_PROTECTION 1

ANTIBIOTIC_TARGET_PROTECTION

Determinant	ARO ID	Organism	Gene families	Evidence
carA	ARO:3002817	not organism-specific	—	ARO:3002817 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.