AntibioticMech

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carbomycin

antibioticmech:aro-27630f7c54 ·ANTIBACTERIAL ·MINTED SEEDED

Produced by Streptomyces halstedii and Streptomyces thermotolerans. — PMID:24542077

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

macrolide antibioticARO:0000000

Strictly broader compounds or drug classes this molecule belongs to.

Chemical structure

Computed structure properties
Molecular formulaC42H67NO16
Charge0
Average mass842.0 Da
Monoisotopic mass841.44598505 Da
SourcePubChem · retrieved 2026-08-29
InChIKeyFQVHOULQCKDUCY-OGHXVOSASA-N

SMILES

C[C@@H]1C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O[C@@H](C[C@H]2[C@@H](O2)/C=C/C1=O)C)OC(=O)C)OC)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C)O[C@H]4C[C@@]([C@H]([C@@H](O4)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O

InChI

InChI=1S/C42H67NO16/c1-21(2)16-32(47)57-40-25(6)53-34(20-42(40,8)50)58-37-24(5)54-41(36(49)35(37)43(9)10)59-38-27(14-15-44)17-22(3)28(46)12-13-29-30(56-29)18-23(4)52-33(48)19-31(39(38)51-11)55-26(7)45/h12-13,15,21-25,27,29-31,34-41,49-50H,14,16-20H2,1-11H3/b13-12+/t22-,23-,24-,25+,27+,29+,30+,31-,34+,35-,36-,37-,38+,39+,40+,41+,42-/m1/s1

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
SourceNative IDLabelMinted CURIEVersion
ARO ARO:3001228 carbomycin antibioticmech:aro-27630f7c54 2026-08-30

Resistance mechanisms

5 source-backed resistance determinants or associations, with ARO grounding where reported. Grouped by reported mechanism type.

ANTIBIOTIC_TARGET_ALTERATION 4
ANTIBIOTIC_TARGET_ALTERATION
DeterminantARO IDOrganismGene familiesEvidence
ErmH ARO:3002823 not organism-specific —
  • ARO:3002823 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)
ErmO-srmA ARO:3001303 not organism-specific —
  • ARO:3001303 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)
ErmS ARO:3001304 not organism-specific —
  • ARO:3001304 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)
ErmV ARO:3002824 not organism-specific —
  • ARO:3002824 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)
ANTIBIOTIC_TARGET_PROTECTION 1
ANTIBIOTIC_TARGET_PROTECTION
DeterminantARO IDOrganismGene familiesEvidence
carA ARO:3002817 not organism-specific —
  • ARO:3002817 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001228 (carbomycin); database assertion, not a primary citation.)

Curation history

  1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Seeded from data/raw/ inventories (ARO)

  2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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