AntibioticMech

cefacetrile

CHEBI:135437 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

Cefacetrile is a broad-spectrum first-generation cephalosporin with antibacterial activity. Cefacetrile binds to and inactivates penicillin-binding proteins located on the inner membrane of the bacterial cell wall causing cell lysis. — PMID:4661097

Classification

cephalosporinARO:0000032

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:23066 CHEBI:23066
• ARO:0000032 ARO:0000032

Chemical structure

Computed structure properties

Molecular formula	C13H13N3O6S
Charge	0
Average mass	339.329 Da
Monoisotopic mass	339.05251 Da
Source	ChEBI
InChIKey	RRYMAQUWDLIUPV-BXKDBHETSA-N

SMILES

[H][C@]12SCC(COC(C)=O)=C(C(=O)O)N1C(=O)[C@H]2NC(=O)CC#N

InChI

InChI=1S/C13H13N3O6S/c1-6(17)22-4-7-5-23-12-9(15-8(18)2-3-14)11(19)16(12)10(7)13(20)21/h9,12H,2,4-5H2,1H3,(H,15,18)(H,20,21)/t9-,12-/m1/s1

Also called

• cefacetrilo (INN)— chebi
• CIBA 36,278A-BA (EXACT_SYNONYM)— chebi
• Cefacetrile (EXACT_SYNONYM)— chebi
• Vetrimast (EXACT_SYNONYM)— chebi
• cefacetrile sodium (EXACT_SYNONYM)— chebi
• cephacetril (EXACT_SYNONYM)— chebi
• cephacetrile (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3009112
• cas:10206-21-0
• drugcentral:524
• hmdb:HMDB0015484
• chembl:CHEMBL2110602
• pubchem.compound:91562

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3009112	cefacetrile	antibioticmech:aro-d2fdce1c82	2026-08-30
CHEBI	CHEBI:135437	cefacetrile	antibioticmech:chebi-d67937f5d8	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO, CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.