cefacetrile

CHEBI:135437 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

Cefacetrile is a broad-spectrum first-generation cephalosporin with antibacterial activity. Cefacetrile binds to and inactivates penicillin-binding proteins located on the inner membrane of the bacterial cell wall causing cell lysis. — PMID:4661097

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

cephalosporinARO:0000032

Strictly broader compounds or drug classes this molecule belongs to.

cephalosporin CHEBI:23066
cephalosporin ARO:0000032

Chemical structure

Computed structure properties
Molecular formula	C13H13N3O6S
Charge	0
Average mass	339.329 Da
Monoisotopic mass	339.05251 Da
Source	ChEBI
InChIKey	RRYMAQUWDLIUPV-BXKDBHETSA-N

SMILES

[H][C@]12SCC(COC(C)=O)=C(C(=O)O)N1C(=O)[C@H]2NC(=O)CC#N

InChI

InChI=1S/C13H13N3O6S/c1-6(17)22-4-7-5-23-12-9(15-8(18)2-3-14)11(19)16(12)10(7)13(20)21/h9,12H,2,4-5H2,1H3,(H,15,18)(H,20,21)/t9-,12-/m1/s1

Also called

cefacetrilo (INN)— chebi
CIBA 36,278A-BA (EXACT_SYNONYM)— chebi
Cefacetrile (EXACT_SYNONYM)— chebi
Vetrimast (EXACT_SYNONYM)— chebi
cefacetrile sodium (EXACT_SYNONYM)— chebi
cephacetril (EXACT_SYNONYM)— chebi
cephacetrile (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

drugcentral:524

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antimicrobial agent CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3009112`	cefacetrile	`antibioticmech:aro-d2fdce1c82`	2026-08-30
CHEBI	`CHEBI:135437`	cefacetrile	`antibioticmech:chebi-d67937f5d8`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO, CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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