ceftezole

CHEBI:135716 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A first-generation cephalosporin antibiotic having (1,3,4-thiadiazol-2-ylsulfanyl)methyl and [2-(1H-tetrazol-1-yl)acetamido side groups located at positions 3 and 7 respectively. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

cephalosporinARO:0000032

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:23066 CHEBI:23066
CHEBI:38099 CHEBI:38099
ARO:0000032 ARO:0000032

Chemical structure

Computed structure properties
Molecular formula	C13H12N8O4S3
Charge	0
Average mass	440.492 Da
Monoisotopic mass	440.01436 Da
Source	ChEBI
InChIKey	DZMVCVMFETWNIU-LDYMZIIASA-N

SMILES

[H][C@]12SCC(CSc3nncs3)=C(C(=O)O)N1C(=O)[C@H]2NC(=O)Cn1cnnn1

InChI

InChI=1S/C13H12N8O4S3/c22-7(1-20-4-14-18-19-20)16-8-10(23)21-9(12(24)25)6(2-26-11(8)21)3-27-13-17-15-5-28-13/h4-5,8,11H,1-3H2,(H,16,22)(H,24,25)/t8-,11-/m1/s1

Also called

ceftezol (INN)— chebi
ceftezolum (INN)— chebi
ceftézole (INN)— chebi
7-[2-(1H-tetrazol-1-yl)acetamido]-3-[(1,3,4-thiadiazol-2-ylsulfanyl)methyl]-3,4-didehydrocepham-4-carboxylic acid (EXACT_SYNONYM)— chebi
(6R,7R)-8-oxo-7-[2-(1H-tetrazol-1-yl)acetamido]-3-[(1,3,4-thiadiazol-2-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (EXACT_SYNONYM)— chebi
demethyl cefazolin (EXACT_SYNONYM)— chebi
demethylcefazolin (EXACT_SYNONYM)— chebi
cephtezole (EXACT_SYNONYM)— aro

Cross-references

Equivalent identifiers for this same structure in other resources.

ARO:3009114
cas:26973-24-0
patent:CN101544659
reaxys:4046849
wikipedia.en:Ceftezole
chembl:CHEMBL1697829
pubchem.compound:65755

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3009114`	ceftezole	`antibioticmech:aro-d6a690cedc`	2026-08-30
CHEBI	`CHEBI:135716`	ceftezole	`antibioticmech:chebi-44d81795f5`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO, CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.