chlorquinaldol

CHEBI:74500 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A monohydroxyquinoline that is quinolin-8-ol which is substituted by a methyl group at position 2 and by chlorine at positions 5 and 7. An antifungal and antibacterial, it was formerly used for topical treatment of skin conditions and vaginal infections. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:36683 CHEBI:36683
CHEBI:38775 CHEBI:38775

Chemical structure

Computed structure properties
Molecular formula	C10H7Cl2NO
Charge	0
Average mass	228.078 Da
Monoisotopic mass	226.99047 Da
Source	ChEBI
InChIKey	GPTXWRGISTZRIO-UHFFFAOYSA-N

SMILES

Cc1ccc2c(Cl)cc(Cl)c(O)c2n1

InChI

InChI=1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3

Also called

chlorquinaldolum (INN)— chebi
clorquinaldol (INN)— chebi
5,7-dichloro-2-methylquinolin-8-ol (EXACT_SYNONYM)— chebi
2-methyl-5,7-dichloro-8-hydroxyquinoline (EXACT_SYNONYM)— chebi
5,7-dichloro-2-methyl-8-hydroxyquinoline (EXACT_SYNONYM)— chebi
5,7-dichloro-2-methyl-8-quinolinol (EXACT_SYNONYM)— chebi
5,7-dichloro-8-hydroxy-2-methylquinoline (EXACT_SYNONYM)— chebi
5,7-dichloro-8-hydroxyquinaldine (EXACT_SYNONYM)— chebi
5,7-dichloro-8-quinaldinol (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:72-80-0
drugcentral:3095
kegg.drug:D07208
patent:US2411670
reaxys:156683
wikipedia.en:Chlorquinaldol

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:35820 CHEBI:35820
CHEBI:36047 CHEBI:36047

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:74500`	chlorquinaldol	`antibioticmech:chebi-f6d4549415`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.