AntibioticMech

colistin B

CHEBI:59673 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A polymyxin having a 6-methylheptanoyl group at the amino terminus. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

nonribosomal peptide antibioticsARO:3009657

Strictly broader compounds or drug classes this molecule belongs to.

Chemical structure

Computed structure properties
Molecular formulaC52H98N16O13
Charge0
Average mass1155.455 Da
Monoisotopic mass1154.74993 Da
SourceChEBI
InChIKeyKNIWPHSUTGNZST-SSWRVQTPSA-N

SMILES

CC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H](C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O

InChI

InChI=1S/C52H98N16O13/c1-27(2)11-9-10-12-40(71)59-32(13-19-53)47(76)68-42(31(8)70)52(81)64-35(16-22-56)44(73)63-37-18-24-58-51(80)41(30(7)69)67-48(77)36(17-23-57)61-43(72)33(14-20-54)62-49(78)38(25-28(3)4)66-50(79)39(26-29(5)6)65-45(74)34(15-21-55)60-46(37)75/h27-39,41-42,69-70H,9-26,53-57H2,1-8H3,(H,58,80)(H,59,71)(H,60,75)(H,61,72)(H,62,78)(H,63,73)(H,64,81)(H,65,74)(H,66,79)(H,67,77)(H,68,76)/t30-,31-,32+,33+,34+,35+,36+,37+,38+,39-,41+,42+/m1/s1

Also called

Cross-references

Equivalent identifiers for this same structure in other resources.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
SourceNative IDLabelMinted CURIEVersion
ARO ARO:3000624 colistin B antibioticmech:aro-1be46b1eac 2026-08-30
CHEBI CHEBI:59673 colistin B antibioticmech:chebi-43ff3c36dc 2026-08-30

Molecular targets

The molecular entity or process this compound acts on. Each target carries evidence — this is a mechanistic claim, not a classification.

cell membrane component targeted by antibiotic MEMBRANE ATTACKED_COMPONENT

ARO:3000710

CARD/ARO database assertion; target organism, strain, and assay are not specified. ARO describes interaction with membrane phospholipids and loss of membrane integrity. Evidence status: DATABASE_ASSERTION_ONLY. Source: CARD_ARO 2026-08-30 (retrieved 2026-08-30).

Resistance mechanisms

123 known routes by which microbes resist this compound, grounded in ARO where CARD models them. Grouped by mechanism type — expand a group to see its determinants.

ANTIBIOTIC_TARGET_ALTERATION 116
ANTIBIOTIC_TARGET_ALTERATION
DeterminantARO IDOrganismGene familiesEvidence
Acinetobacter mutant Lpx gene conferring resistance to colistin ARO:3003581 not organism-specific —
  • ARO:3003581 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
ArnT ARO:3005053 not organism-specific —
  • ARO:3005053 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
ICR-Mc ARO:3004466 not organism-specific —
  • ARO:3004466 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
ICR-Mo ARO:3004569 not organism-specific —
  • ARO:3004569 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
Klebsiella mutant PhoP conferring antibiotic resistance to colistin ARO:3003585 not organism-specific —
  • ARO:3003585 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
LpxA ARO:3003573 not organism-specific —
  • ARO:3003573 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
LpxC ARO:3003574 not organism-specific —
  • ARO:3003574 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
LpxD ARO:3003575 not organism-specific —
  • ARO:3003575 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR phosphoethanolamine transferase ARO:3004268 not organism-specific —
  • ARO:3004268 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.1 ARO:3003689 not organism-specific —
  • ARO:3003689 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.10 ARO:3004506 not organism-specific —
  • ARO:3004506 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.11 ARO:3004688 not organism-specific —
  • ARO:3004688 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.12 ARO:3004689 not organism-specific —
  • ARO:3004689 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.13 ARO:3004690 not organism-specific —
  • ARO:3004690 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.14 ARO:3007246 not organism-specific —
  • ARO:3007246 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.15 ARO:3007279 not organism-specific —
  • ARO:3007279 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.16 ARO:3007238 not organism-specific —
  • ARO:3007238 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.17 ARO:3007244 not organism-specific —
  • ARO:3007244 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.18 ARO:3007233 not organism-specific —
  • ARO:3007233 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.19 ARO:3007240 not organism-specific —
  • ARO:3007240 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.2 ARO:3004194 not organism-specific —
  • ARO:3004194 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.20 ARO:3007235 not organism-specific —
  • ARO:3007235 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.21 ARO:3007237 not organism-specific —
  • ARO:3007237 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.22 ARO:3007239 not organism-specific —
  • ARO:3007239 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.23 ARO:3007234 not organism-specific —
  • ARO:3007234 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.24 ARO:3007243 not organism-specific —
  • ARO:3007243 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.25 ARO:3007247 not organism-specific —
  • ARO:3007247 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.26 ARO:3007280 not organism-specific —
  • ARO:3007280 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.27 ARO:3007232 not organism-specific —
  • ARO:3007232 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.28 ARO:3007236 not organism-specific —
  • ARO:3007236 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.29 ARO:3007241 not organism-specific —
  • ARO:3007241 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.3 ARO:3004514 not organism-specific —
  • ARO:3004514 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.30 ARO:3007242 not organism-specific —
  • ARO:3007242 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.31 ARO:3007245 not organism-specific —
  • ARO:3007245 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.32 ARO:3007289 not organism-specific —
  • ARO:3007289 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.33 ARO:3007070 not organism-specific —
  • ARO:3007070 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.34 ARO:3007230 not organism-specific —
  • ARO:3007230 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.4 ARO:3004515 not organism-specific —
  • ARO:3004515 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.5 ARO:3004685 not organism-specific —
  • ARO:3004685 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.6 ARO:3004513 not organism-specific —
  • ARO:3004513 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.7 ARO:3004686 not organism-specific —
  • ARO:3004686 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.8 ARO:3004687 not organism-specific —
  • ARO:3004687 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-1.9 ARO:3004507 not organism-specific —
  • ARO:3004507 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-10.2 ARO:3007277 not organism-specific —
  • ARO:3007277 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-10.3 ARO:3007275 not organism-specific —
  • ARO:3007275 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-10.4 ARO:3007276 not organism-specific —
  • ARO:3007276 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-10.5 ARO:3007274 not organism-specific —
  • ARO:3007274 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-2.1 ARO:3004110 not organism-specific —
  • ARO:3004110 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-2.2 ARO:3004502 not organism-specific —
  • ARO:3004502 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-2.3 ARO:3007284 not organism-specific —
  • ARO:3007284 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-2.4 ARO:3007283 not organism-specific —
  • ARO:3007283 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-2.5 ARO:3007286 not organism-specific —
  • ARO:3007286 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-2.6 ARO:3007288 not organism-specific —
  • ARO:3007288 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-2.7 ARO:3007287 not organism-specific —
  • ARO:3007287 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-2.8 ARO:3007285 not organism-specific —
  • ARO:3007285 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.1 ARO:3004139 not organism-specific —
  • ARO:3004139 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.10 ARO:3004504 not organism-specific —
  • ARO:3004504 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.11 ARO:3004500 not organism-specific —
  • ARO:3004500 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.12 ARO:3004693 not organism-specific —
  • ARO:3004693 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.13 ARO:3007269 not organism-specific —
  • ARO:3007269 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.14 ARO:3007249 not organism-specific —
  • ARO:3007249 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.15 ARO:3007252 not organism-specific —
  • ARO:3007252 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.16 ARO:3007260 not organism-specific —
  • ARO:3007260 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.17 ARO:3007278 not organism-specific —
  • ARO:3007278 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.18 ARO:3007263 not organism-specific —
  • ARO:3007263 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.19 ARO:3007273 not organism-specific —
  • ARO:3007273 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.2 ARO:3004511 not organism-specific —
  • ARO:3004511 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.20 ARO:3007266 not organism-specific —
  • ARO:3007266 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.21 ARO:3007262 not organism-specific —
  • ARO:3007262 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.22 ARO:3007259 not organism-specific —
  • ARO:3007259 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.23 ARO:3007256 not organism-specific —
  • ARO:3007256 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.24 ARO:3007265 not organism-specific —
  • ARO:3007265 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.25 ARO:3007258 not organism-specific —
  • ARO:3007258 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.26 ARO:3007261 not organism-specific —
  • ARO:3007261 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.27 ARO:3007253 not organism-specific —
  • ARO:3007253 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.28 ARO:3007270 not organism-specific —
  • ARO:3007270 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.29 ARO:3007272 not organism-specific —
  • ARO:3007272 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.3 ARO:3004662 not organism-specific —
  • ARO:3004662 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.31 ARO:3007255 not organism-specific —
  • ARO:3007255 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.32 ARO:3007254 not organism-specific —
  • ARO:3007254 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.33 ARO:3007248 not organism-specific —
  • ARO:3007248 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.34 ARO:3007268 not organism-specific —
  • ARO:3007268 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.35 ARO:3007267 not organism-specific —
  • ARO:3007267 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.36 ARO:3007257 not organism-specific —
  • ARO:3007257 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.37 ARO:3007250 not organism-specific —
  • ARO:3007250 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.38 ARO:3007251 not organism-specific —
  • ARO:3007251 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.39 ARO:3007271 not organism-specific —
  • ARO:3007271 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.4 ARO:3004691 not organism-specific —
  • ARO:3004691 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.40 ARO:3007264 not organism-specific —
  • ARO:3007264 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.41 ARO:3005221 not organism-specific —
  • ARO:3005221 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.5 ARO:3004505 not organism-specific —
  • ARO:3004505 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.6 ARO:3004503 not organism-specific —
  • ARO:3004503 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.7 ARO:3004510 not organism-specific —
  • ARO:3004510 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.8 ARO:3004509 not organism-specific —
  • ARO:3004509 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-3.9 ARO:3004508 not organism-specific —
  • ARO:3004508 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-4.1 ARO:3004325 not organism-specific —
  • ARO:3004325 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-4.2 ARO:3004694 not organism-specific —
  • ARO:3004694 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-4.3 ARO:3004695 not organism-specific —
  • ARO:3004695 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-4.4 ARO:3004696 not organism-specific —
  • ARO:3004696 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-4.5 ARO:3004697 not organism-specific —
  • ARO:3004697 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-4.6 ARO:3007231 not organism-specific —
  • ARO:3007231 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-4.7 ARO:3007533 not organism-specific —
  • ARO:3007533 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-5.1 ARO:3004332 not organism-specific —
  • ARO:3004332 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-5.2 ARO:3004698 not organism-specific —
  • ARO:3004698 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-5.3 ARO:3007282 not organism-specific —
  • ARO:3007282 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-5.4 ARO:3007281 not organism-specific —
  • ARO:3007281 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-6.1 ARO:3004501 not organism-specific —
  • ARO:3004501 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-7.1 ARO:3004517 not organism-specific —
  • ARO:3004517 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-8.1 ARO:3004516 not organism-specific —
  • ARO:3004516 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-8.2 ARO:3007229 not organism-specific —
  • ARO:3007229 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-8.3 ARO:3007227 not organism-specific —
  • ARO:3007227 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-8.4 ARO:3007228 not organism-specific —
  • ARO:3007228 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MCR-9.1 ARO:3004684 not organism-specific —
  • ARO:3004684 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
almEFG ARO:3007434 not organism-specific —
  • ARO:3007434 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
eptB ARO:3005047 not organism-specific —
  • ARO:3005047 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
mcr-10.1 ARO:3007137 not organism-specific —
  • ARO:3007137 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
ANTIBIOTIC_EFFLUX 5
ANTIBIOTIC_EFFLUX
DeterminantARO IDOrganismGene familiesEvidence
Klebsiella pneumoniae KpnEF ARO:3004585 not organism-specific —
  • ARO:3004585 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
Klebsiella pneumoniae mutant PhoQ conferring resistance to colistin ARO:3007203 not organism-specific —
  • ARO:3007203 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
MexAB-OprM ARO:3000386 not organism-specific —
  • ARO:3000386 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
Pseudomonas mutant PhoP conferring resistance to colistin ARO:3003895 not organism-specific —
  • ARO:3003895 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
Pseudomonas mutant PhoQ conferring resistance to colistin ARO:3003896 not organism-specific —
  • ARO:3003896 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
REDUCED_PERMEABILITY 1
REDUCED_PERMEABILITY
DeterminantARO IDOrganismGene familiesEvidence
LpsB ARO:3005051 not organism-specific —
  • ARO:3005051 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)
UNKNOWN 1
UNKNOWN
DeterminantARO IDOrganismGene familiesEvidence
mgrB ARO:3003820 not organism-specific —
  • ARO:3003820 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3000624 (colistin B); database assertion, not a primary citation.)

Curation history

  1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Seeded from data/raw/ inventories (ARO, CHEBI)

  2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  4. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.