conessine

CHEBI:27965 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A steroid alkaloid that is con-5-enine substituted by a N,N-dimethylamino group at position 3. It has been isolated from the plant species of the family Apocynaceae. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:26767 CHEBI:26767
CHEBI:50996 CHEBI:50996

Chemical structure

Computed structure properties
Molecular formula	C24H40N2
Charge	0
Average mass	356.598 Da
Monoisotopic mass	356.31915 Da
Source	ChEBI
InChIKey	GPLGAQQQNWMVMM-MYAJQUOBSA-N

SMILES

[H][C@@]12CC=C3C[C@@H](N(C)C)CC[C@]3(C)[C@@]1([H])CC[C@]13CN(C)[C@@H](C)[C@@]1([H])CC[C@@]23[H]

InChI

InChI=1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1

Also called

N,N-dimethylcon-5-enin-3β-amine (EXACT_SYNONYM)— chebi
Conessine (EXACT_SYNONYM)— chebi
Conessinum (EXACT_SYNONYM)— chebi
Neriine (EXACT_SYNONYM)— chebi
Roquessine (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:546-06-5
kegg.compound:C06545
knapsack:C00002243
reaxys:4702160
wikipedia.en:Conessine

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33282 CHEBI:33282
CHEBI:38068 CHEBI:38068

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:27965`	conessine	`antibioticmech:chebi-a420a7f356`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.