AntibioticMech

decatromicin A

CHEBI:65728 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A carbohydrate-containing antibiotic isolated from Actinomadura sp. MK73-NF4. It specifically inhibits the growth of gram-positive bacteria including multi-drug resistant strains such as Staphylococcus aureus MS9610 and menthicilin-resistant S.aureus (MRSA). — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:23007 CHEBI:23007
• CHEBI:25384 CHEBI:25384
• CHEBI:26455 CHEBI:26455
• CHEBI:32988 CHEBI:32988
• CHEBI:36683 CHEBI:36683
• CHEBI:37581 CHEBI:37581
• CHEBI:37948 CHEBI:37948
• CHEBI:3992 CHEBI:3992
• CHEBI:51026 CHEBI:51026
• CHEBI:63349 CHEBI:63349

Chemical structure

Computed structure properties

Molecular formula	C45H57ClN2O10
Charge	0
Average mass	821.408 Da
Monoisotopic mass	820.37017 Da
Source	ChEBI
InChIKey	YKLXDAWPGVZXKC-NMNDIUEASA-N

SMILES

[H][C@]12C=C[C@@]3([H])C/C=C/C/C(C)=C/[C@@]4(C)C=C(C(=O)O)[C@@H](CC)C[C@]45OC(=O)C(=C5O)C(=O)[C@@]3(CC)[C@]1([H])CC[C@H](C)[C@]2([H])O[C@H]1C[C@@H](O)[C@H](NC(=O)c2nccc2Cl)[C@@H](C)O1

InChI

InChI=1S/C45H57ClN2O10/c1-7-26-21-45-39(51)34(42(55)58-45)38(50)44(8-2)27(12-10-9-11-23(3)20-43(45,6)22-29(26)41(53)54)14-15-28-30(44)16-13-24(4)37(28)57-33-19-32(49)35(25(5)56-33)48-40(52)36-31(46)17-18-47-36/h9-10,14-15,17-18,20,22,24-28,30,32-33,35,37,47,49,51H,7-8,11-13,16,19,21H2,1-6H3,(H,48,52)(H,53,54)/b10-9+,23-20+/t24-,25+,26-,27+,28-,30+,32+,33-,35+,37-,43-,44+,45+/m0/s1

Also called

• (3S,4S,4aS,6aR,8E,11E,12aS,15S,16aS,20aR,20bR)-4-[(4-{[(3-chloro-1H-pyrrol-2-yl)carbonyl]amino}-2,4,6-trideoxy-β-D-arabino-hexopyranosyl)oxy]-15,20a-diethyl-21-hydroxy-3,11,12a-trimethyl-18,20-dioxo-1,2,3,4,4a,6a,7,10,12a,15,16,20,20a,20b-tetradecahydro-16a,19-(metheno)benzo[b]naphtho[2,1-j]oxacyclotetradecine-14(18H)-carboxylic acid (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• reaxys:8469607

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33281 CHEBI:33281
• CHEBI:33282 CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:65728	decatromicin A	antibioticmech:chebi-1673537741	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.