diflunisal
CHEBI:39669
·resolve ·ANTIBACTERIAL
·EXACT
SEEDED
Diflunisal is a salicylic acid derivative and aspirin analogue typically used as a nonsteroidal anti-inflammatory drug. It has been shown to exhibit antibiotic activity against Escherichia coli by inhibiting MurA (MurZ), thereby disrupting cell wall synthesis. — PMID:35453279
Machine-generated and unreviewed. Identity, structure and
cross-references come straight from ChEBI's and CARD's own data; no curator has
signed off on this record yet.
Classification
salicylic acid antibioticARO:3007159
Strictly broader compounds or drug classes this molecule belongs to.
Chemical structure
Computed structure properties
| Molecular formula | C13H8F2O3 |
|---|
| Charge | 0 |
|---|
| Average mass | 250.2 Da |
|---|
| Monoisotopic mass | 250.04415 Da |
|---|
| Source | ChEBI |
|---|
| InChIKey | HUPFGZXOMWLGNK-UHFFFAOYSA-N |
|---|
SMILES
O=C(O)c1cc(-c2ccc(F)cc2F)ccc1O
InChI
InChI=1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)
Also called
- Adomal (EXACT_SYNONYM)— aro
- Dolobid (EXACT_SYNONYM)— aro
- Dolobis (EXACT_SYNONYM)— aro
- Flovacil (EXACT_SYNONYM)— aro
- Fluniget (EXACT_SYNONYM)— aro
- Fluodonil (EXACT_SYNONYM)— aro
- Flustar (EXACT_SYNONYM)— aro
Cross-references
Equivalent identifiers for this same structure in other resources.
Source concepts
Every upstream concept that resolved to this record. The merge is
the product: this is what shows ChEBI and CARD are describing the same structure.
Upstream concepts merged into this record
| Source | Native ID | Label | Minted CURIE | Version |
|---|
| ARO |
ARO:3007091 |
diflunisal |
antibioticmech:aro-4da855baac |
2026-08-30 |
Mechanism summary
- Clinical status
- APPROVED
Curation history
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SEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
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RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
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RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
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RESEEDED_FROM_SOURCES
2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
Provenance
Seeded by scripts/seed_from_sources.py from the committed
inventories in data/raw/.
View the record.