erdasporine B

CHEBI:156314 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An organic heterohexacyclic compound that is 12,13-dihydro-6H-indolo[2,3-a]pyrrolo[3,4-c]carbazole in which the hydrogen at position 5 is substituted by a methoxycarbonyl group. It is synthesized by a gene cluster found in environmental DNA and exhibits cytotoxic activity against human HCT116 cancer cells and Staphylococcus aureus. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:25248 CHEBI:25248
CHEBI:37697 CHEBI:37697
CHEBI:50995 CHEBI:50995
CHEBI:51914 CHEBI:51914

Chemical structure

Computed structure properties
Molecular formula	C22H15N3O2
Charge	0
Average mass	353.381 Da
Monoisotopic mass	353.11643 Da
Source	ChEBI
InChIKey	POAWNROCPSHGIZ-UHFFFAOYSA-N

SMILES

COC(=O)c1ncc2c1c1c3ccccc3nc1c1nc3ccccc3c21

InChI

InChI=1S/C22H15N3O2/c1-27-22(26)21-18-13(10-23-21)16-11-6-2-4-8-14(11)24-19(16)20-17(18)12-7-3-5-9-15(12)25-20/h2-10,23-25H,1H3

Also called

methyl 12,13-dihydro-6H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5-carboxylate (EXACT_SYNONYM)— chebi
methyl 3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1(16),2(10),4,6,8,11,14,17,19,21-decaene-12-carboxylate (EXACT_SYNONYM)— chebi

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33282 CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:156314`	erdasporine B	`antibioticmech:chebi-b921915631`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.