AntibioticMech

etimicin

CHEBI:134705 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An aminoglycoside antibiotic that is gentamycin C1a in which the hydrogen of the amino group at position 1 is substituted by an ethyl group. It is a fourth generation semisynthetic aminoglycoside that has antimicrobial activity against both gram-positive and gram-negative bacterial infections and also effective against aminoglycoside resistant strains. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:22479 CHEBI:22479
• CHEBI:22507 CHEBI:22507

Chemical structure

Computed structure properties

Molecular formula	C21H43N5O7
Charge	0
Average mass	477.603 Da
Monoisotopic mass	477.31625 Da
Source	ChEBI
InChIKey	NZGMVSJQULXLHF-RAKCNUBFSA-N

SMILES

CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@](C)(O)[C@H](NC)[C@H]1O

InChI

InChI=1S/C21H43N5O7/c1-4-26-13-7-12(24)16(32-19-11(23)6-5-10(8-22)31-19)14(27)17(13)33-20-15(28)18(25-3)21(2,29)9-30-20/h10-20,25-29H,4-9,22-24H2,1-3H3/t10-,11+,12-,13+,14-,15+,16+,17-,18+,19+,20+,21-/m0/s1

Also called

• (1R,2S,3S,4R,6S)-6-amino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]oxy}-4-(ethylamino)-2-hydroxycyclohexyl 2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranoside (EXACT_SYNONYM)— chebi
• 1-N-ethylgentamicin C1a (EXACT_SYNONYM)— chebi
• N1-ethylgentamicin C1a (EXACT_SYNONYM)— chebi
• antibiotic 89-07 (EXACT_SYNONYM)— chebi
• etilmicin (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:59711-96-5
• drugcentral:5171
• patent:US5814488

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33281 CHEBI:33281
• CHEBI:33282 CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:134705	etimicin	antibioticmech:chebi-a90eb7c313	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.