factumycin

antibioticmech:aro-fdb0f4de1c ·ANTIBACTERIAL ·MINTED SEEDED

Factumycin is a kirromycin-like antibiotic produced by Kitasatospora setae and Streptomyces strains. Its biosynthetic cluster has been characterized which has interesting acetyl transferase domains in trans, or outside of the polyketide synthase domains. Factumycin has specific, rather than broad spectrum, antibacterial properties, especially targeting various Acinetobacter baumanii strains. — PMID:7166535

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

elfamycin antibioticARO:3001219

Strictly broader compounds or drug classes this molecule belongs to.

ARO:3001219 ARO:3001219

Chemical structure

Computed structure properties
Molecular formula	C44H62N2O10
Charge	0
Average mass	779.0 Da
Monoisotopic mass	778.44044618 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	HMBDLBWGDMNPDW-SUXULKRESA-N

SMILES

CCC(C(=O)NC/C=C/C=C(/C)\[C@@H]([C@@H](C)C([C@H](/C=C\C=C\C=C\C=C(/C)\C(=O)C1=C(C=CN(C1=O)C)O)O)O)OC)[C@@]2(C[C@@H](C([C@@H](O2)/C=C/C=C\C)(C)C)O)O

InChI

InChI=1S/C44H62N2O10/c1-10-12-16-24-36-43(6,7)35(49)28-44(54,56-36)32(11-2)41(52)45-26-20-19-22-30(4)40(55-9)31(5)39(51)34(48)23-18-15-13-14-17-21-29(3)38(50)37-33(47)25-27-46(8)42(37)53/h10,12-25,27,31-32,34-36,39-40,47-49,51,54H,11,26,28H2,1-9H3,(H,45,52)/b12-10-,15-13+,17-14+,20-19+,23-18-,24-16+,29-21+,30-22-/t31-,32?,34-,35-,36-,39?,40-,44-/m0/s1

Cross-references

Equivalent identifiers for this same structure in other resources.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3001220`	factumycin	`antibioticmech:aro-fdb0f4de1c`	2026-08-30

Resistance mechanisms

1 known routes by which microbes resist this compound, grounded in ARO where CARD models them. Grouped by mechanism type — expand a group to see its determinants.

ANTIBIOTIC_EFFLUX 1

ANTIBIOTIC_EFFLUX
Determinant	ARO ID	Organism	Gene families	Evidence
facT	ARO:3001313	not organism-specific	—	ARO:3001313 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001220 (factumycin); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.