fellutanine

CHEBI:70168 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by 1H-indol-3-ylmethyl groups at positions 3 and 6 respectively. Isolated from Penicillium species, it exhibits antibacterial activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:38958
Label unavailable CHEBI:65061

Chemical structure

Computed structure properties
Molecular formula	C22H20N4O2
Charge	0
Average mass	372.428 Da
Monoisotopic mass	372.15863 Da
Source	ChEBI
InChIKey	DNHODRZUCGXYKU-BGYRXZFFSA-N

SMILES

O=C1N[C@H](Cc2cnc3ccccc23)C(=O)N[C@H]1Cc1cnc2ccccc12

InChI

InChI=1S/C22H20N4O2/c27-21-19(9-13-11-23-17-7-3-1-5-15(13)17)25-22(28)20(26-21)10-14-12-24-18-8-4-2-6-16(14)18/h1-8,11-12,19-20,23-24H,9-10H2,(H,25,28)(H,26,27)/t19-,20+

Also called

(3R,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione (EXACT_SYNONYM)— chebi
cyclo(Trp-Trp) (EXACT_SYNONYM)— chebi
cyclo-(L-Trp-D-Trp) (EXACT_SYNONYM)— chebi
fellutanine A (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

reaxys:8651145

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antibacterial agent CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:70168`	fellutanine	`antibioticmech:chebi-23bf202db7`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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