Formicamycin congeners are promising antibiotics with potent activity against Gram-positive pathogens including VRE and MRSA and display a high barrier to selection of resistant isolates.
Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.
polyketide with antibiotic activityARO:3005171
ARO:3005171| Molecular formula | C30H27Cl3O8 |
|---|---|
| Charge | 0 |
| Average mass | 621.9 Da |
| Monoisotopic mass | 620.077151 Da |
| Source | PubChem · retrieved 2026-08-29 |
| InChIKey | ITMXZWXSZNBZAO-HZAQMHFWSA-N |
CC1=C(C(=CC(=C1Cl)OC)OC)C2=CC(=C(C3=C2C(=O)[C@@]4([C@H](C3)C(C5=C(C4=O)C(=CC(=C5Cl)O)O)(C)C)O)Cl)OC
InChI=1S/C30H27Cl3O8/c1-11-20(16(39-4)10-18(41-6)24(11)31)12-7-17(40-5)25(32)13-8-19-29(2,3)23-22(14(34)9-15(35)26(23)33)28(37)30(19,38)27(36)21(12)13/h7,9-10,19,34-35,38H,8H2,1-6H3/t19-,30-/m1/s1
| Source | Native ID | Label | Minted CURIE | Version |
|---|---|---|---|---|
| ARO | ARO:3007585 |
formicamycin E | antibioticmech:aro-d39089d50d |
2026-08-30 |
Seeded from data/raw/ inventories (ARO)
Re-seeded from updated data/raw/ inventories
Re-seeded from updated data/raw/ inventories