AntibioticMech

furagin

CHEBI:131714 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [3-(5-nitro-2-furyl)prop-2-en-1-ylidene]amino group (the configuration of the C=C and C=N bonds in the grouping that links the two heterocycles is not specified). A nitrofuran antibiotic with properties similar to nitrofurantoin, furagin is used in the treatment of urinary tract infections. — ChEBI

Classification

nitrofuran antibioticARO:3004116

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:24628 CHEBI:24628
• CHEBI:25558 CHEBI:25558
• CHEBI:25807 CHEBI:25807
• CHEBI:87230 CHEBI:87230
• ARO:3004116 ARO:3004116

Chemical structure

Computed structure properties

Molecular formula	C10H8N4O5
Charge	0
Average mass	264.197 Da
Monoisotopic mass	264.04947 Da
Source	ChEBI
InChIKey	DECBQELQORZLLP-UHFFFAOYSA-N

SMILES

O=C1CN(N=CC=Cc2ccc([N+](=O)[O-])o2)C(=O)N1

InChI

InChI=1S/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)

Also called

• Akritoin (BRAND_NAME)— chebi
• Furagin (BRAND_NAME)— chebi
• 1-{[3-(5-nitro-2-furyl)prop-2-en-1-ylidene]amino}imidazolidine-2,4-dione (EXACT_SYNONYM)— chebi
• 1-((3-(5-nitro-2-furyl)allylidene)amino)-hydantoin (EXACT_SYNONYM)— chebi
• NF 416 (EXACT_SYNONYM)— chebi
• NF-416 (EXACT_SYNONYM)— chebi
• NF416 (EXACT_SYNONYM)— chebi
• furazidin (EXACT_SYNONYM)— chebi
• furazidine (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3007677
• cas:1672-88-4
• drugcentral:4869
• kegg.drug:D07998
• patent:WO9841520
• reaxys:307076
• chembl:CHEMBL3707254
• pubchem.compound:6870646

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33281 CHEBI:33281
• CHEBI:36047 CHEBI:36047

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3007677	furazidin	antibioticmech:aro-dfdd8033b4	2026-08-30
CHEBI	CHEBI:131714	furagin	antibioticmech:chebi-f46e5b09e1	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO, CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.