furaltadone

CHEBI:74803 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An oxazolidinone that is 1,3-oxazolidin-2-one substituted at position 1 by a (5-nitro-2-furyl)methylene]amino group and at position 5 by a morpholin-4-ylmethyl group. An antibacterial formerly used oraly but withdrawn due to toxicity, it is used topically (as the hydrochloride salt) for treatment of ear disorders. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:24129 CHEBI:24129
CHEBI:35716 CHEBI:35716
CHEBI:38785 CHEBI:38785
CHEBI:55374 CHEBI:55374

Chemical structure

Computed structure properties
Molecular formula	C13H16N4O6
Charge	0
Average mass	324.293 Da
Monoisotopic mass	324.10698 Da
Source	ChEBI
InChIKey	YVQVOQKFMFRVGR-UHFFFAOYSA-N

SMILES

[H]C(=NN1CC(CN2CCOCC2)OC1=O)c1ccc([N+](=O)[O-])o1

InChI

InChI=1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2

Also called

Altafur (BRAND_NAME)— chebi
furaltadona (INN)— chebi
furaltadonum (INN)— chebi
5-(morpholin-4-ylmethyl)-3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one (EXACT_SYNONYM)— chebi
5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)oxazolidone (EXACT_SYNONYM)— chebi
5-morpholinomethyl-3-(5-nitro-2-furfurylidine-amino)-2-oxazolidinone (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:139-91-3
kegg.drug:D02510
lincs.smallmolecule:LSM-5034
patent:CN101497609
patent:US2802002
reaxys:363627

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:36047 CHEBI:36047

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:74803`	furaltadone	`antibioticmech:chebi-64a80bc514`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.