AntibioticMech

furazolidone

CHEBI:5195 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera. — ChEBI

Classification

nitrofuran antibioticARO:3004116

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:38329 CHEBI:38329
• CHEBI:87230 CHEBI:87230
• ARO:3004116 ARO:3004116

Chemical structure

Computed structure properties

Molecular formula	C8H7N3O5
Charge	0
Average mass	225.16 Da
Monoisotopic mass	225.03857 Da
Source	ChEBI
InChIKey	PLHJDBGFXBMTGZ-UHFFFAOYSA-N

SMILES

[H]C(=NN1CCOC1=O)c1ccc([N+](=O)[O-])o1

InChI

InChI=1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2

Also called

• Furazolidona (INN)— chebi
• Furazolidonum (INN)— chebi
• 3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one (EXACT_SYNONYM)— chebi
• 3-(5'-Nitrofurfuralamino)-2-oxazolidone (EXACT_SYNONYM)— chebi
• 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone (EXACT_SYNONYM)— chebi
• 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidone (EXACT_SYNONYM)— chebi
• 3-[(5-Nitrofurylidene)amino]-2-oxazolidone (EXACT_SYNONYM)— chebi
• 3-{[(5-Nitro-2-furanyl)methylene]amino}-2-oxazolidinone (EXACT_SYNONYM)— chebi
• 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine (EXACT_SYNONYM)— chebi
• FZL (EXACT_SYNONYM)— chebi
• Furazolidone (EXACT_SYNONYM)— chebi
• Furoxone (EXACT_SYNONYM)— chebi
• N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone (EXACT_SYNONYM)— chebi
• N-(5-Nitro-2-furfurylidene)-3-aminooxazolidine-2-one (EXACT_SYNONYM)— chebi
• Nitrofurazolidone (EXACT_SYNONYM)— chebi
• Nitrofurazolidonum (EXACT_SYNONYM)— chebi
• furazolidine (EXACT_SYNONYM)— aro
• furoxone (EXACT_SYNONYM)— aro
• nitrofurazolidone (EXACT_SYNONYM)— aro

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3000688
• cas:67-45-8
• drugbank:DB00614
• drugcentral:1257
• hmdb:HMDB0014752
• kegg.compound:C07999
• kegg.drug:D00830
• lincs.smallmolecule:LSM-6543
• patent:GB735136
• patent:US2742462
• patent:US2759931
• patent:US2927110
• reaxys:384794
• wikipedia.en:Furazolidone
• chembl:CHEMBL1103
• pubchem.compound:5323714

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33281 CHEBI:33281
• CHEBI:36047 CHEBI:36047
• CHEBI:50685 CHEBI:50685

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3000688	furazolidone	antibioticmech:aro-f1250d6591	2026-08-30
CHEBI	CHEBI:5195	furazolidone	antibioticmech:chebi-75d9ff26dd	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO, CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.