AntibioticMech

gepotidacin

antibioticmech:aro-b2e68d25c8 ·ANTIBACTERIAL ·MINTED SEEDED

Gepotidacin is a triazaacenaphthylene bacterial type II topoisomerase inhibitor used experimentally. It has been in phase III of clinical trials since 2019 for the treatment of gonorrhea, however gepotidacin has demonstrated antibiotic activity against a variety of bacteria. — PMID:26729499

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

triazaacenaphthylene antibioticARO:3007164

Strictly broader compounds or drug classes this molecule belongs to.

Chemical structure

Computed structure properties
Molecular formulaC24H28N6O3
Charge0
Average mass448.5 Da
Monoisotopic mass448.22228878 Da
SourcePubChem · retrieved 2026-08-29
InChIKeyPZFAZQUREQIODZ-LJQANCHMSA-N

SMILES

C1CC2=CC(=NC=C2OC1)CNC3CCN(CC3)C[C@@H]4CN5C(=O)C=CC6=C5N4C(=O)C=N6

InChI

InChI=1S/C24H28N6O3/c31-22-4-3-20-24-29(22)15-19(30(24)23(32)13-27-20)14-28-7-5-17(6-8-28)25-11-18-10-16-2-1-9-33-21(16)12-26-18/h3-4,10,12-13,17,19,25H,1-2,5-9,11,14-15H2/t19-/m1/s1

Cross-references

Equivalent identifiers for this same structure in other resources.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
SourceNative IDLabelMinted CURIEVersion
ARO ARO:3007092 gepotidacin antibioticmech:aro-b2e68d25c8 2026-08-30

Curation history

  1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Seeded from data/raw/ inventories (ARO)

  2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.