gepotidacin

antibioticmech:aro-b2e68d25c8 ·ANTIBACTERIAL ·MINTED SEEDED

Gepotidacin is a triazaacenaphthylene bacterial type II topoisomerase inhibitor used experimentally. It has been in phase III of clinical trials since 2019 for the treatment of gonorrhea, however gepotidacin has demonstrated antibiotic activity against a variety of bacteria. — PMID:26729499

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

triazaacenaphthylene antibioticARO:3007164

Strictly broader compounds or drug classes this molecule belongs to.

triazaacenaphthylene antibiotic ARO:3007164

Chemical structure

Computed structure properties
Molecular formula	C24H28N6O3
Charge	0
Average mass	448.5 Da
Monoisotopic mass	448.22228878 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	PZFAZQUREQIODZ-LJQANCHMSA-N

SMILES

C1CC2=CC(=NC=C2OC1)CNC3CCN(CC3)C[C@@H]4CN5C(=O)C=CC6=C5N4C(=O)C=N6

InChI

InChI=1S/C24H28N6O3/c31-22-4-3-20-24-29(22)15-19(30(24)23(32)13-27-20)14-28-7-5-17(6-8-28)25-11-18-10-16-2-1-9-33-21(16)12-26-18/h3-4,10,12-13,17,19,25H,1-2,5-9,11,14-15H2/t19-/m1/s1

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3007092`	gepotidacin	`antibioticmech:aro-b2e68d25c8`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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