AntibioticMech

griseofulvin

CHEBI:27779 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:36683 CHEBI:36683
• CHEBI:37948 CHEBI:37948
• CHEBI:38830 CHEBI:38830
• CHEBI:87113 CHEBI:87113
• CHEBI:87128 CHEBI:87128

Chemical structure

Computed structure properties

Molecular formula	C17H17ClO6
Charge	0
Average mass	352.77 Da
Monoisotopic mass	352.07137 Da
Source	ChEBI
InChIKey	DDUHZTYCFQRHIY-RBHXEPJQSA-N

SMILES

COC1=CC(=O)C[C@@H](C)[C@]12Oc1c(Cl)c(OC)cc(OC)c1C2=O

InChI

InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

Also called

• Curling factor (BRAND_NAME)— chebi
• Fulcin (BRAND_NAME)— chebi
• Fulvicin (BRAND_NAME)— chebi
• Grifulvin (BRAND_NAME)— chebi
• Grisactin (BRAND_NAME)— chebi
• Grisovin (BRAND_NAME)— chebi
• Grysio (BRAND_NAME)— chebi
• Lamoryl (BRAND_NAME)— chebi
• Likuden (BRAND_NAME)— chebi
• Poncyl (BRAND_NAME)— chebi
• Spirofulvin (BRAND_NAME)— chebi
• Sporostatin (BRAND_NAME)— chebi
• griseofulvina (INN)— chebi
• griseofulvinum (INN)— chebi
• griséofulvine (INN)— chebi
• (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione (EXACT_SYNONYM)— chebi
• (+)-griseofulvin (EXACT_SYNONYM)— chebi
• Griseofulvin (EXACT_SYNONYM)— chebi
• amudane (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:126-07-8
• drugbank:DB00400
• drugcentral:1331
• kegg.compound:C06686
• kegg.drug:D00209
• knapsack:C00002398
• lincs.smallmolecule:LSM-5259
• lipidmaps:LMPK13060001
• metacyc.compound:CPD-17786
• patent:US3069328
• patent:US3069329
• ppdb:1807
• reaxys:95226
• vsdb:1807
• wikipedia.en:Griseofulvin

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33282 CHEBI:33282
• CHEBI:35718 CHEBI:35718
• CHEBI:86327 CHEBI:86327

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:27779	griseofulvin	antibioticmech:chebi-42f55b6feb	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.