griseofulvin

CHEBI:27779 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:36683
Label unavailable CHEBI:37948
Label unavailable CHEBI:38830
antibiotic antifungal drug CHEBI:87113
benzofuran antifungal drug CHEBI:87128

Chemical structure

Computed structure properties
Molecular formula	C17H17ClO6
Charge	0
Average mass	352.77 Da
Monoisotopic mass	352.07137 Da
Source	ChEBI
InChIKey	DDUHZTYCFQRHIY-RBHXEPJQSA-N

SMILES

COC1=CC(=O)C[C@@H](C)[C@]12Oc1c(Cl)c(OC)cc(OC)c1C2=O

InChI

InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

Also called

Curling factor (BRAND_NAME)— chebi
Fulcin (BRAND_NAME)— chebi
Fulvicin (BRAND_NAME)— chebi
Grifulvin (BRAND_NAME)— chebi
Grisactin (BRAND_NAME)— chebi
Grisovin (BRAND_NAME)— chebi
Grysio (BRAND_NAME)— chebi
Lamoryl (BRAND_NAME)— chebi
Likuden (BRAND_NAME)— chebi
Poncyl (BRAND_NAME)— chebi
Spirofulvin (BRAND_NAME)— chebi
Sporostatin (BRAND_NAME)— chebi
griseofulvina (INN)— chebi
griseofulvinum (INN)— chebi
griséofulvine (INN)— chebi
(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione (EXACT_SYNONYM)— chebi
(+)-griseofulvin (EXACT_SYNONYM)— chebi
Griseofulvin (EXACT_SYNONYM)— chebi
amudane (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antibacterial agent CHEBI:33282
antifungal agent CHEBI:35718
antifungal drug CHEBI:86327

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:27779`	griseofulvin	`antibioticmech:chebi-42f55b6feb`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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