AntibioticMech

Browse · ANTIBACTERIAL

Hispidulin

antibioticmech:curator-b453af7884 ·ANTIBACTERIAL ·MINTED PROPOSED

A flavonoid with antibacterial activity against drug-resistant bacterial pathogens. — DOI:10.1128/spectrum.02374-25

Chemical structure

Computed structure properties
Molecular formulaC16H12O6
Charge0
Average mass300.26 Da
Monoisotopic mass300.0633881 Da
Sourcehttps://pubchem.ncbi.nlm.nih.gov/compound/5281628 · retrieved 2026-09-07
InChIKeyIHFBPDAQLQOCBX-UHFFFAOYSA-N

SMILES

COC1=C(C2=C(C=C1O)OC(=CC2=O)C3=CC=C(C=C3)O)O

InChI

InChI=1S/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
SourceNative IDLabelMinted CURIEVersionEvidence
CURATOR DOI:10.1128/spectrum.02374-25#hispidulin Hispidulin antibioticmech:curator-b453af7884 2026-09-07
  • DOI:10.1128/spectrum.02374-25 — "Zai et al. reported hispidulin among six Terminalia flavonoids that inhibited growth of both methicillin- and beta-lactam-resistant bacterial pathogens." (PubChem CID 5281628 supplies the standard InChI, InChIKey, formula, and SMILES for hispidulin.)

Curation history

  1. PROPOSED_FROM_CURATOR_INVENTORY 2026-09-08 · seed_from_sources

    Proposed from curation/curator_antibiotics.tsv

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (Hispidulin) · CultureMech · NaturalProductMech · PathwayMech · TraitMech