lucensimycin E

CHEBI:66592 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An organic heterotetracyclic compound isolated from the bacterial strain Streptomyces lucensis MA7349 and has been shown to exhibit antibacterial activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:16385 CHEBI:16385
CHEBI:22160 CHEBI:22160
CHEBI:35692 CHEBI:35692
CHEBI:37948 CHEBI:37948
CHEBI:38163 CHEBI:38163
CHEBI:47622 CHEBI:47622
CHEBI:50361 CHEBI:50361

Chemical structure

Computed structure properties
Molecular formula	C34H41NO12S
Charge	0
Average mass	687.764 Da
Monoisotopic mass	687.23495 Da
Source	ChEBI
InChIKey	PTLQDKFYOYMVQN-CECFYEBASA-N

SMILES

[H][C@]12C[C@@H](OC(C)=O)[C@H](C)[C@@H](O)[C@]1([H])C=C[C@@]1([H])C[C@@H](/C=C/C=C/C=C/C(=O)O)[C@@]3(C(=O)O[C@H](CSC[C@@H](NC(C)=O)C(=O)O)C3=O)C(=O)[C@]21C

InChI

InChI=1S/C34H41NO12S/c1-17-25(46-19(3)37)14-23-22(28(17)40)12-11-20-13-21(9-7-5-6-8-10-27(38)39)34(31(44)33(20,23)4)29(41)26(47-32(34)45)16-48-15-24(30(42)43)35-18(2)36/h5-12,17,20-26,28,40H,13-16H2,1-4H3,(H,35,36)(H,38,39)(H,42,43)/b6-5+,9-7+,10-8+/t17-,20-,21+,22+,23-,24+,25+,26+,28+,33-,34-/m0/s1

Also called

(2E,4E,6E)-7-[(2'S,3R,4a'S,4b'S,5S,6'R,7'R,8'S,8a'R,10a'R)-5-({[(2S)-2-(acetylamino)-2-carboxyethyl]sulfanyl}methyl)-6'-(acetyloxy)-8'-hydroxy-4a',7'-dimethyl-2,4,4'-trioxo-1',4,4',4a',4b',5,5',6',7',8',8a',10a'-dodecahydro-2'H-spiro[furan-3,3'-phenanthren]-2'-yl]hepta-2,4,6-trienoic acid (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

reaxys:19619266

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281
CHEBI:33282 CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:66592`	lucensimycin E	`antibioticmech:chebi-67d861c321`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.