LYS228

antibioticmech:aro-00a588048a ·ANTIBACTERIAL ·MINTED SEEDED

A monobactam with potent activity against Enterobacteriaceae. Stable to metallo-B-lactamases and serine carbapenemases resulting in potency against the majority of extended-spectrum B-lactamase-producing and carbapenem-resistant Enterobacteriaceae strains tested. — PMID:30038040

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

monobactamARO:0000004

Strictly broader compounds or drug classes this molecule belongs to.

monobactam ARO:0000004

Chemical structure

Computed structure properties
Molecular formula	C16H18N6O10S2
Charge	0
Average mass	518.5 Da
Monoisotopic mass	518.05258314 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	FWTGYTRQUBRVDW-UWGJAOEXSA-N

SMILES

C1CC1(C(=O)O)O/N=C(\C2=CSC(=N2)N)/C(=O)N[C@H]3[C@H](N(C3=O)S(=O)(=O)O)CN4CCOC4=O

InChI

InChI=1S/C16H18N6O10S2/c17-14-18-7(6-33-14)9(20-32-16(1-2-16)13(25)26)11(23)19-10-8(5-21-3-4-31-15(21)27)22(12(10)24)34(28,29)30/h6,8,10H,1-5H2,(H2,17,18)(H,19,23)(H,25,26)(H,28,29,30)/b20-9+/t8-,10+/m1/s1

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

LYS228ARO:3004729
pubchem.compound:118380292

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3004729`	LYS228	`antibioticmech:aro-00a588048a`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (LYS228) · CultureMech · NaturalProductMech · PathwayMech · TraitMech