AntibioticMech

marbofloxacin

CHEBI:132230 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A fluoroquinolone antibiotic that is 7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline substituted at positions 6, 9 and 10 by carboxy, fluoro and 4-methylpiperazin-1-yl groups, respectively. A synthetic, broad spectrum bactericidal agent, it is used in veterinary medicine, although its mechanism of action is not thoroughly understood. — ChEBI

Classification

fluoroquinolone antibioticARO:0000001

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:25384 CHEBI:25384
• CHEBI:46845 CHEBI:46845
• CHEBI:83575 CHEBI:83575
• CHEBI:87211 CHEBI:87211
• ARO:0000001 ARO:0000001

Chemical structure

Computed structure properties

Molecular formula	C16H17FN4O4
Charge	0
Average mass	348.334 Da
Monoisotopic mass	348.12338 Da
Source	ChEBI
InChIKey	LPVVTHNMXSEIFM-UHFFFAOYSA-N

SMILES

CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2OCN4)CC1

InChI

InChI=1S/C16H17FN4O4/c1-19-2-4-20(5-3-19)13-11(17)6-9-12-15(13)25-8-18-21(12)7-10(14(9)22)16(23)24/h6-7,18H,2-5,8H2,1H3,(H,23,24)

Also called

• marbofloxacine (INN)— chebi
• marbofloxacino (INN)— chebi
• marbofloxacinum (INN)— chebi
• 9-fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic acid (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3007046
• cas:115550-35-1
• lincs.smallmolecule:LSM-5799
• wikipedia.en:Marbofloxacin
• chembl:CHEMBL478120
• pubchem.compound:60651

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33281 CHEBI:33281
• CHEBI:36047 CHEBI:36047

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3007046	marbofloxacin	antibioticmech:aro-59c1e98f75	2026-08-30
CHEBI	CHEBI:132230	marbofloxacin	antibioticmech:chebi-f3a683401d	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO, CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.