AntibioticMech

mycinamicin IV

CHEBI:63284 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A mycinamicin composed of a 16-membered ring macrolactone core, an N,N-dimethylated deoxysugar desosamine and a 2,3-di-O-methylated 6-deoxysugar mycinose. — ChEBI

Classification

macrolide antibioticARO:0000000

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:63276 CHEBI:63276
• ARO:0000000 ARO:0000000

Chemical structure

Computed structure properties

Molecular formula	C37H61NO11
Charge	0
Average mass	695.891 Da
Monoisotopic mass	695.42446 Da
Source	ChEBI
InChIKey	DBTIHDIIXPQOFR-JMHKOBKLSA-N

SMILES

CC[C@H]1OC(=O)/C=C/[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@@H](C)C[C@@H](C)C(=O)/C=C/C=C/[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]1OC

InChI

InChI=1S/C37H61NO11/c1-11-29-26(20-45-37-35(44-10)34(43-9)31(41)25(6)47-37)14-12-13-15-28(39)22(3)18-23(4)33(21(2)16-17-30(40)48-29)49-36-32(42)27(38(7)8)19-24(5)46-36/h12-17,21-27,29,31-37,41-42H,11,18-20H2,1-10H3/b14-12+,15-13+,17-16+/t21-,22+,23-,24+,25+,26+,27-,29+,31+,32+,33+,34+,35+,36-,37+/m0/s1

Also called

• [(2R,3R,4E,6E,9R,11S,12S,13S,14E)-2-ethyl-9,11,13-trimethyl-8,16-dioxo-12-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}oxacyclohexadeca-4,6,14-trien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-β-D-allopyranoside (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3001224
• pubchem.compound:6447311

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3001224	mycinamicin	antibioticmech:aro-fe60dfd405	2026-08-30
CHEBI	CHEBI:63284	mycinamicin IV	antibioticmech:chebi-c4a3b14f93	2026-08-30

Resistance mechanisms

4 known routes by which microbes resist this compound, grounded in ARO where CARD models them. Grouped by mechanism type — expand a group to see its determinants.

ANTIBIOTIC_TARGET_ALTERATION 3

ANTIBIOTIC_TARGET_ALTERATION

Determinant	ARO ID	Organism	Gene families	Evidence
RlmA(II)	ARO:3001301	not organism-specific	—	ARO:3001301 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001224 (mycinamicin); database assertion, not a primary citation.)
chrB	ARO:3001302	not organism-specific	—	ARO:3001302 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001224 (mycinamicin); database assertion, not a primary citation.)
myrA	ARO:3001300	not organism-specific	—	ARO:3001300 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001224 (mycinamicin); database assertion, not a primary citation.)

ANTIBIOTIC_TARGET_PROTECTION 1

ANTIBIOTIC_TARGET_PROTECTION

Determinant	ARO ID	Organism	Gene families	Evidence
tlrC	ARO:3002827	not organism-specific	—	ARO:3002827 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001224 (mycinamicin); database assertion, not a primary citation.)

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO, CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

4. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.