A C-8-methoxy non-fluorinated quinolone exhibiting potent antibacterial activities against Gram-positive, including MRSA and fluoroquinolone-resistant MRSA, Gram-negative, and atypical pathogens, especially methicillin-resistant Staphylococcus aureus.
Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.
fluoroquinolone antibioticARO:0000001
ARO:0000001| Molecular formula | C20H25N3O4 |
|---|---|
| Charge | 0 |
| Average mass | 371.437 Da |
| Monoisotopic mass | 371.18451 Da |
| Source | ChEBI |
| InChIKey | AVPQPGFLVZTJOR-RYUDHWBXSA-N |
COc1c(N2C[C@@H](C)C[C@H](N)C2)ccc2c(=O)c(C(=O)O)cn(C3CC3)c12
InChI=1S/C20H25N3O4/c1-11-7-12(21)9-22(8-11)16-6-5-14-17(19(16)27-2)23(13-3-4-13)10-15(18(14)24)20(25)26/h5-6,10-13H,3-4,7-9,21H2,1-2H3,(H,25,26)/t11-,12-/m0/s1
| Source | Native ID | Label | Minted CURIE | Version |
|---|---|---|---|---|
| ARO | ARO:3004733 |
nemonoxacin | antibioticmech:aro-2a44e3ab23 |
2026-08-30 |
Seeded from data/raw/ inventories (ARO, CHEBI)
Re-seeded from updated data/raw/ inventories
Re-seeded from updated data/raw/ inventories