nitazoxanide

antibioticmech:aro-f198f10971 ·ANTIBACTERIAL ·MINTED SEEDED

Nitazoxanide is a thiazolide antiparatasitic and antiviral drug that has demonstrated antibacterial activity against Helicobacter pylori. It is well tolerated and exhibits a synergistic effect with other antibiotics, such as clarithromycin. — PMID:35587063

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

thiazolide antibioticARO:3007177

Strictly broader compounds or drug classes this molecule belongs to.

thiazolide antibiotic ARO:3007177

Chemical structure

Computed structure properties
Molecular formula	C12H9N3O5S
Charge	0
Average mass	307.28 Da
Monoisotopic mass	307.02629157 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	YQNQNVDNTFHQSW-UHFFFAOYSA-N

SMILES

CC(=O)OC1=CC=CC=C1C(=O)NC2=NC=C(S2)[N+](=O)[O-]

InChI

InChI=1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17)

Also called

Alinia (EXACT_SYNONYM)— aro
Nizonide (EXACT_SYNONYM)— aro
nitazoxamide (EXACT_SYNONYM)— aro

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3007178`	nitazoxanide	`antibioticmech:aro-f198f10971`	2026-08-30

Mechanism summary

Clinical status: APPROVED

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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