oridonin

CHEBI:138236 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An organic heteropentacyclic compound and ent-kaurane diterpenoid with formula C20H28O6 isolated from the leaves of the medicinal herb Rabdosia rubescens. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:35681 CHEBI:35681
CHEBI:36760 CHEBI:36760
CHEBI:38164 CHEBI:38164
CHEBI:51689 CHEBI:51689
CHEBI:59780 CHEBI:59780

Chemical structure

Computed structure properties
Molecular formula	C20H28O6
Charge	0
Average mass	364.438 Da
Monoisotopic mass	364.18859 Da
Source	ChEBI
InChIKey	SDHTXBWLVGWJFT-XKCURVIJSA-N

SMILES

[H][C@]12CC[C@H]3[C@@]45CO[C@](O)([C@@H](O)[C@]4([H])C(C)(C)CC[C@@H]5O)[C@@]3(C(=O)C1=C)[C@@H]2O

InChI

InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13+,15+,16-,18+,19-,20+/m0/s1

Also called

(1α,5β,6β,7α,8α,9β,10α,13α,14R)-1,6,7,14-tetrahydroxy-7,20-epoxykaur-16-en-15-one (EXACT_SYNONYM)— chebi
(1α,6β,7α,14R)-7,20-epoxy-1,6,7,14-tetrahydroxykaur-16-en-15-one (EXACT_SYNONYM)— chebi
isodonol (EXACT_SYNONYM)— chebi
oridonine (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:28957-04-2
knapsack:C00033270
reaxys:1691227

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33282 CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:138236`	oridonin	`antibioticmech:chebi-11ffc9a7da`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.