AntibioticMech

ornidazole

CHEBI:75176 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 3-chloro-2-hydroxypropyl and methyl groups, respectively. It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections. — ChEBI

Classification

nitroimidazole antibioticARO:3004115

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:24780 CHEBI:24780
• CHEBI:35681 CHEBI:35681
• CHEBI:35716 CHEBI:35716
• CHEBI:36683 CHEBI:36683
• ARO:3004115 ARO:3004115

Chemical structure

Computed structure properties

Molecular formula	C7H10ClN3O3
Charge	0
Average mass	219.628 Da
Monoisotopic mass	219.04107 Da
Source	ChEBI
InChIKey	IPWKIXLWTCNBKN-UHFFFAOYSA-N

SMILES

Cc1ncc([N+](=O)[O-])n1CC(O)CCl

InChI

InChI=1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3

Also called

• ornidazol (INN)— chebi
• ornidazolum (INN)— chebi
• 1-chloro-3-(2-methyl-5-nitro-1N-imidazol-1-yl)propan-2-ol (EXACT_SYNONYM)— chebi
• 1-(2-hydroxy-3-chloropropyl)-2-methyl-5-nitroimidazole (EXACT_SYNONYM)— chebi
• 1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole (EXACT_SYNONYM)— chebi
• Ro 7-0207 (EXACT_SYNONYM)— chebi
• α-(Chlormethyl)-2-methyl-5-nitro-imidazol-1-aethanol (EXACT_SYNONYM)— chebi
• α-(chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3007114
• cas:16773-42-5
• drugcentral:1997
• kegg.drug:D05274
• lincs.smallmolecule:LSM-1548
• patent:NL6606853
• patent:US3435049
• patent:US3493582
• reaxys:614299
• wikipedia.en:Ornidazole
• chembl:CHEMBL1449676
• pubchem.compound:28061

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:35820 CHEBI:35820
• CHEBI:36047 CHEBI:36047
• CHEBI:50685 CHEBI:50685

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3007114	ornidazole	antibioticmech:aro-91924bc338	2026-08-30
CHEBI	CHEBI:75176	ornidazole	antibioticmech:chebi-e9b38cb3ee	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO, CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.