AntibioticMech

phenelfamycin E

antibioticmech:aro-0ae735fe08 ·ANTIBACTERIAL ·MINTED SEEDED

Phenelfamycin E was isolated from two environmental isolates called AB999F-80 and AB1047T-33. They were both identified as Streptomyces violaceoniger strains. Both these strains were found to produce phenelfamycins A-F and unphenelfamycin. Phenelfamycin E has a trisaccaride moeity and is isomeric with phenelfamycin F. All phenelfamycins were selected due to their activity against anaerobic bacteria, especially Clostridioides difficile. Phenelfamycin E and F are the most potent of the phenelfamycins. — PMID:3192490

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

elfamycin antibioticARO:3001219

Strictly broader compounds or drug classes this molecule belongs to.

Chemical structure

Computed structure properties
Molecular formulaC65H95NO21
Charge0
Average mass1226.4 Da
Monoisotopic mass1225.63965904 Da
SourcePubChem · retrieved 2026-08-29
InChIKeyUDVVGDCMWCVRCO-CUFFYTIGSA-N

SMILES

CC=CC=C[C@H]1C([C@H]([C@H]([C@](O1)(C(CO[C@@H]2C[C@H](C([C@H](O2)C)O[C@H]3C[C@@H]([C@@H]([C@H](O3)C)O[C@@H]4C[C@H]([C@H]([C@H](O4)C)O)OC)OC)OC)C(=O)NCC=CC=C(C)C([C@@H](C)C5C[C@H]([C@H](O5)C=CC=CC=CC(=O)O)O)OC)O)OC(=O)CC6=CC=CC=C6)O)(C)C

InChI

InChI=1S/C65H95NO21/c1-13-14-18-29-51-64(7,8)61(72)62(84-53(70)32-43-26-19-17-20-27-43)65(74,87-51)44(63(73)66-31-24-23-25-38(2)58(78-12)39(3)47-33-45(67)46(83-47)28-21-15-16-22-30-52(68)69)37-79-54-35-49(76-10)59(41(5)81-54)86-56-36-50(77-11)60(42(6)82-56)85-55-34-48(75-9)57(71)40(4)80-55/h13-30,39-42,44-51,54-62,67,71-72,74H,31-37H2,1-12H3,(H,66,73)(H,68,69)/t39-,40+,41+,42+,44?,45+,46+,47?,48+,49+,50-,51-,54-,55+,56-,57-,58?,59?,60+,61-,62+,65+/m0/s1

Cross-references

Equivalent identifiers for this same structure in other resources.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
SourceNative IDLabelMinted CURIEVersion
ARO ARO:3001253 phenelfamycin E antibioticmech:aro-0ae735fe08 2026-08-30

Curation history

  1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Seeded from data/raw/ inventories (ARO)

  2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.