phomalevone A

CHEBI:68297 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A biaryl that is 5,5',10a,10a'-tetrahydro-9H,9'H-2,2'-bixanthene-9,9'-dione substituted by hydroxy groups at positions 1, 1', 5, 5', 8 and 8' and methyl groups at positions 3, 3', 10a and 10a'. Isolated from the cultures of a Hawaiian isolate of the fungus Phoma species, it exhibits antibacterial activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:26188 CHEBI:26188
CHEBI:26195 CHEBI:26195
CHEBI:51149 CHEBI:51149
CHEBI:64459 CHEBI:64459

Chemical structure

Computed structure properties
Molecular formula	C30H26O10
Charge	0
Average mass	546.528 Da
Monoisotopic mass	546.1526 Da
Source	ChEBI
InChIKey	KMDRWTGFZLUZEY-NEUGYGHLSA-N

SMILES

Cc1cc2c(c(O)c1-c1c(C)cc3c(c1O)C(=O)C1=C(O)C=C[C@H](O)[C@]1(C)O3)C(=O)C1=C(O)C=C[C@H](O)[C@]1(C)O2

InChI

InChI=1S/C30H26O10/c1-11-9-15-21(27(37)23-13(31)5-7-17(33)29(23,3)39-15)25(35)19(11)20-12(2)10-16-22(26(20)36)28(38)24-14(32)6-8-18(34)30(24,4)40-16/h5-10,17-18,31-36H,1-4H3/t17-,18-,29-,30-/m0/s1

Also called

(5S,5'S,10aR,10a'R)-1,1',5,5',8,8'-hexahydroxy-3,3',10a,10a'-tetramethyl-5,5',10a,10a'-tetrahydro-9H,9'H-2,2'-bixanthene-9,9'-dione (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

reaxys:21389531

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33282 CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:68297`	phomalevone A	`antibioticmech:chebi-998472b8a7`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.